Category Archives: Prevention, Engagement and Care Cascade
Pharmacy-based interventions to increase use of HIV pre-exposure prophylaxis in the United States: A scoping review
HIV pre-exposure prophylaxis (PrEP) remains underutilized in the U.S. Since greater than 85% of PrEP prescriptions are filled at commercial pharmacies, pharmacists are uniquely positioned to increase PrEP use. This...
NK cell-based therapies for HIV infection: Investigating current advances and future possibilities
NK cells are well-known for their antiviral functions. Also, their role in HIV has been well established, with rapid responses elicited during early HIV infection. Most immune cells including CD4(+)...
Testing for saturation in qualitative evidence syntheses: An update of HIV adherence in Africa
BACKGROUND: A systematic review of randomised trials may be conclusive signalling no further research is needed; or identify gaps requiring further research that may then be included in review updates....
Post-immigration factors affecting retention in HIV care and viral suppression in Latin American and Caribbean immigrant populations in the United States: A systematic review
Objectives: To reduce disparities in HIV care outcomes among Latin American and Caribbean (LAC) immigrants living with HIV in the U.S., it is necessary to identify factors influencing HIV care in...
Non-vertical exposures to HIV, HBV and HCV infection in children and adolescents-risk of infection, standards of care and postexposure prophylaxis
INTRODUCTION: in the review, we aimed to present current knowledge about the risk of infection, standards of care, and postexposure prophylaxis (PEP) in pediatric patients after non-vertical exposures to HIV,...
Coordinating systems of care for HIV and opioid use disorder: A systematic review of enablers and barriers to integrated service access, and systems and tools required for implementation
Individuals who have HIV who also use drugs experience increased age-matched morbidity and mortality in comparison with those with HIV who do not use drugs. A systematic review was conducted...
An update on neuropsychiatric adverse effects with second-generation integrase inhibitors and nonnucleoside reverse transcriptase inhibitors
PURPOSE OF REVIEW: Neuropsychiatric adverse effects (NPAE) associated with integrase strand transfer inhibitors (INSTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) are a growing concern, with higher rates in the real-world...
Cause of hospitalization and death in the antiretroviral era in Sub-Saharan Africa published 2008–2018: A systematic review
BACKGROUND: Worldwide despite the availability of antiretroviral therapy, human immunodeficiency virus/acquired immunodeficiency syndrome still causes morbidity and mortality among patients. In Sub-Saharan Africa, human immunodeficiency virus/acquired immunodeficiency syndrome remains a...
Novel platforms for biomedical HIV prevention delivery to key populations — Community mobile clinics, peer-supported, pharmacy-led PrEP delivery, and the use of telemedicine
PURPOSE OF REVIEW: A gap exists between PrEP interest and PrEP uptake in key populations (KP) for HIV prevention that may be ascribed to PrEP delivery services not being acceptable....
Improving post-release care engagement for people living with HIV involved in the criminal justice system: A systematic review
Given sub-optimal HIV care outcomes for people living with HIV (PLWH) post-release from incarceration, we systematically searched peer-reviewed literature (2010–2021) describing controlled trial interventions aimed at improving Antiretroviral Therapy (ART)...
Perinatal outcomes in women living with HIV-1 and receiving antiretroviral therapy — A systematic review and meta-analysis
Introduction Antiretroviral therapy-naïve pregnant women living with HIV are at an increased risk for adverse pregnancy outcomes. It remains controversial whether this risk persists with antiretroviral therapy. We conducted a...
