Category Archives: Prevention, Engagement and Care Cascade
Systematic review and meta-analysis of treatment interruptions in human immunodeficiency virus (HIV) type 1-infected patients receiving antiretroviral therapy: Implications for future HIV cure trials
BACKGROUND: Safety and tolerability of analytical treatment interruptions (ATIs) as a vital part of human immunodeficiency virus type 1 (HIV-1) cure studies are discussed. We analyzed current evidence for the...
A review of reported cases of HIV pre-exposure prophylaxis failure with resultant breakthrough HIV infections
OBJECTIVES: Early randomized controlled trials (RCTs) have confirmed high efficacy of pre-exposure prophylaxis (PrEP) for preventing HIV infection in men who have sex with men (MSM) with high HIV exposure...
Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: A systematic review and meta-analysis
Background and aim: Globally, nearly one in five people who inject drugs (PWID) are living with HIV, and the rate of new HIV infections in PWID is increasing in some...
Optimization Models for HIV/AIDS Resource Allocation: A systematic review
OBJECTIVE: This study reviews optimization models for human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) resource allocation. METHODS: We searched 2 databases for peer-reviewed articles published from January 1985...
Poor treatment outcome and its predictors among drug-resistant tuberculosis patients in Ethiopia: A systematic review and meta-analysis
OBJECTIVE: To assess poor treatment outcomes and their predictors among drug-resistant tuberculosis patients treated in Ethiopia. METHODS: Data were searched from both electronic databases and other sources. From the whole...
Global Research on Quality of Life of Patients with HIV/AIDS: Is It Socio-Culturally Addressed? (GAP(RESEARCH))
Quality of life (QOL) has been considered as an important outcome indicator in holistic care for HIV-infected people, especially as HIV/AIDS transforms from a fatal illness to a chronic condition....
Clinical impact of pretreatment human immunodeficiency virus drug resistance in people initiating nonnucleoside reverse transcriptase inhibitor-containing antiretroviral therapy: A systematic review and meta-analysis
BACKGROUND: Increased access to antiretroviral therapy (ART) has resulted in rising levels of pretreatment human immunodeficiency virus drug resistance (PDR). This is the first systematic review and meta-analysis to assess...
Recruitment of US adolescents and young adults (AYA) into human immunodeficiency virus (HIV)-related behavioral research studies: A scoping review
PURPOSE OF REVIEW: The objective of this scoping review was to examine the range of published evidence on recruitment approaches and outcomes of US adolescents and young adults (AYA) ages...
The LAIs are coming! implementation science considerations for long-acting injectable antiretroviral therapy in the United States: A scoping review
Long-acting injectable antiretroviral therapy (LAI-ART) is one of the latest advancements in HIV control with the potential to overcome oral ART barriers to adherence. The objective of this article is...
A systematic review of transfusion-transmissible infections among blood donors and associated safety challenges in Pakistan
The blood transfusion (BT) system in Pakistan is fragmented, demand-driven and depends on weakly regulated transfusion practices. There is a considerable possibility that transfusion-transmissible infections (TTIs) are contributing to the...