Category Archives: Prevention, Engagement and Care Cascade
Structural interventions for HIV prevention and care among US men who have sex with men: A systematic review of evidence, gaps, and future priorities
The preponderance of HIV interventions have been behavioral, targeting individual, dyadic, or group dynamics. However, structural-level interventions are required to decrease HIV transmission and increase engagement in care, especially for...
Effectiveness and safety of dolutegravir two-drug regimens in virologically suppressed people living with HIV: A systematic literature review and meta-analysis of real-world evidence
Objectives: Dolutegravir (DTG) is widely recommended within three-drug regimens. However, similar efficacy and tolerability have also been achieved with DTG within two-drug regimens in clinical trials. This study evaluated the real-world...
A systematic review of early adoption of implementation science for HIV prevention or treatment in the United States
OBJECTIVE: To provide the first systematic review of the early adoption of implementation science for HIV prevention or treatment in the United States. We identified primary research studies that addressed...
Missed opportunities for sexually transmitted infections testing for HIV pre-exposure prophylaxis users: A systematic review
Introduction: Given the synergistic relationship between HIV and sexually transmitted infections (STI), the integration of services has the potential to reduce the incidence of both HIV and STIs. We explored the...
Youth engagement in HIV prevention intervention research in sub-Saharan Africa: A scoping review
INTRODUCTION: Youth engagement in HIV research is generally recognized as essential, but often neglected or minimally implemented in practice. Engagement is a process of working collaboratively with diverse groups of...
Barriers and facilitators to pre-exposure prophylaxis among African migrants in high income countries: A systematic review
BACKGROUND: The aim of this review is to explore acceptability, barriers, and facilitators to PrEP use among African migrants in high-income countries. METHODS: A systematic review was conducted to explore...
HIV self-testing uptake and intervention strategies among men in Sub-Saharan Africa: A systematic review
Background: HIV testing is an essential gateway to HIV prevention and treatment services. However, HIV testing uptake remains low among men due to stigma, discrimination, and confidentiality concerns. HIV self-testing...
Cabotegravir-Rilpivirine: The first complete long-acting injectable regimen for the treatment of HIV-1 infection
OBJECTIVE: To review the efficacy and safety of cabotegravir (CAB) with rilpivirine (RPV) in the treatment of HIV-1 infection. DATA SOURCES: A literature search was performed using PubMed and Google...
mHealth strategies related to HIV postexposure prophylaxis knowledge and access: Systematic literature review, technology prospecting of patent databases, and systematic search on app stores
BACKGROUND: Globally, the number of HIV cases continue to increase, despite the development of multiple prevention strategies. New cases of HIV have been reported disproportionately more in men who have...
Global burden of active smoking among people living with HIV on antiretroviral therapy: A systematic review and meta-analysis
Background: Although the high burden of both active smoking and human immunodeficiency virus (HIV) is clearly known, the relationship between them is still not well characterized. Therefore, we estimated the...
Impact of advanced HIV disease on quality of life and mortality in the era of combined antiretroviral treatment
Currently, AIDS or severe immunodeficiency remains as a challenge for people with HIV (PWHIV) and healthcare providers. Our purpose was to analyze the impact of advanced HIV disease (AHD) on...
