Category Archives: Prevention

Recent evidence for emerging digital technologies to support global HIV engagement in care

2015

Antiretroviral therapy is a powerful tool to reduce morbidity and mortality for the 35 million people living with HIV globally. However, availability of treatment alone is insufficient to meet new...

Revisiting the understanding of “transactional sex” in sub-Saharan Africa: A review and synthesis of the literature

2016

In sub-Saharan Africa, young women ages 15-24 have more than twice the risk of acquiring HIV as their male counterparts. A growing body of epidemiological evidence suggests that the practice...

Effectiveness of pharmacy-based needle/syringe exchange programme for people who inject drugs: A systematic review and meta-analysis

2016

AIMS: To appraise the evidence critically for effectiveness of pharmacy-based needle/syringe exchange programmes (pharmacy-based NSPs) on risk behaviours (RBs), HIV/HCV prevalence and economic outcomes among people who inject drugs (PWID)....

Interventions to prevent sexually transmitted infections, including HIV, among young people in low- and middle-income countries: A systematic review of the published and gray literature

2016

Sexually transmitted infections (STIs), including HIV, are prevalent among adolescents and can have lasting adverse health consequences. The objective of this review is to identify high-quality interventions and evaluations to...

How do HIV-negative individuals in sub-Saharan Africa change their sexual risk behaviour upon learning their serostatus? A systematic review

2016

OBJECTIVE: To determine whether, and how, sexual behaviour of HIV-negative individuals in sub-Saharan Africa (SSA) changes upon learning their serostatus. METHODS: We systematically reviewed the published literature using EMBASE and...

Hepatitis B and A vaccination in HIV-infected adults: A review

2015

Hepatitis B and A account for considerable morbidity and mortality worldwide. Immunization is the most effective means of preventing hepatitis B and A. However, the immune response to both hepatitis...

Equality in sexual health promotion: a systematic review of effective interventions for black and minority ethnic men who have sex with men

2016

BACKGROUND: Over the past decade, new diagnoses of HIV have increased eightfold among men who have sex with men (MSM) of other or of mixed ethnicity in the UK. Yet...

Effectiveness of semen washing to prevent human immunodeficiency virus (HIV) transmission and assist pregnancy in HIV-discordant couples: A systematic review and meta-analysis

2016

OBJECTIVE: To evaluate the effectiveness of semen washing in human immunodeficiency virus (HIV)-discordant couples in which the male partner is infected. DESIGN: Systematic review and meta-analysis. SETTING: Not applicable. PATIENT(S):...

The effect of HIV counselling and testing on HIV acquisition in sub-Saharan Africa: A systematic review

2016

OBJECTIVES: Annually, millions of people in sub-Saharan Africa (SSA) receive HIV counselling and testing (HCT), a service designed to inform persons of their HIV status and, if HIV uninfected, reduce...

Suboptimal viral suppression rates among HIV-infected children in low- and middle-income countries: A meta-analysis

2016

BACKGROUND: The 90-90-90 goals aim to achieve viral suppression in 90% of all HIV-infected people on antiretroviral treatment (ART), which is especially challenging in children. Global estimates of viral suppression...

Comparing psychosocial correlates of condomless anal sex in HIV-diagnosed and HIV-nondiagnosed men who have sex with men: A series of meta-analyses of studies from 1993–2013

2015

PURPOSE: Men who have sex with men (MSM) continue to be overrepresented in rates of incidence and prevalence of human immunodeficiency virus (HIV). Both HIV-diagnosed (HIV-D) and HIV-nondiagnosed (HIV-N) MSM...

Preventing HIV-1 infection in women using oral pre-exposure prophylaxis: A meta-analysis of current evidence

2016

The World Health Organization has issued an early release revision to its antiretroviral guidelines in which PrEP (pre-exposure prophylaxis in the form of daily oral, fixed dose combination tenofovir disoproxil...

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