Category Archives: Prevention
Factors affecting adherence to short-course ARV prophylaxis for preventing mother-to-child transmission of HIV in sub-Saharan Africa: A review and lessons for future elimination
Despite the biomedical potential to eliminate vertical HIV transmission, drug adherence to short regimens is often sub-optimal. To inform future programmes, we reviewed evidence on the factors influencing maternal and...
Nonoxynol-9 for preventing vaginal acquisition of sexually transmitted infections by women from men
BACKGROUND: The incidence and prevalence of sexually transmitted infections (STI) and other reproductive tract infections (RTI) is high in much of the developing and parts of the developed worlds. STIs...
Helping our patients take HIV pre-exposure prophylaxis (PrEP): A systematic review of adherence interventions
OBJECTIVES: Adherence is critical for maximizing the effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV infection. Strategies for promoting adherence to HIV treatment, and their potential application to PrEP adherence,...
Meta-analytical studies on the epidemiology, prevention, and treatment of human immunodeficiency virus infection
Since the beginning of the epidemic, extensive research has been conducted in the field of HIV infection. Original research and subsequent meta-analyses have contributed to a better understanding of the...
Vaginal microbicides for preventing mother-to-child transmission of HIV infection – No evidence of an effect or evidence of no effect?
BACKGROUND: Vaginal disinfection is a simple, potentially effective strategy for reducing mother-to-child transmission (MTCT) of HIV that can be implemented in combination with antiretroviral therapy or even in the absence...
Socioeconomic status as a risk factor for HIV infection in women in East, Central and Southern Africa: A systematic review
This is a critical, systematic review of the relationship between socioeconomic status (SES) and HIV infection in women in Southern, Central and Eastern Africa. In light of the interest in...
Randomized controlled trials of individual-level, population-level, and multilevel interventions for preventing sexually transmitted infections: What has worked?
BACKGROUND: Previous reviews of interventions to prevent sexually transmitted infections (STIs) focused mostly on human immunodeficiency virus (HIV) infection. We reviewed trials of interventions to prevent sexual transmission of any...
Highly active antiretroviral therapy and sexual risk behavior: A meta-analytic review
Context: Evidence suggests that since highly active antiretroviral therapy (HAART) became available, the prevalence of unprotected sex and the incidence of sexually transmitted infections (STIs) have increased. Objective: To conduct...
School based sex education and HIV prevention in low- and middle-income countries: A systematic review and meta-analysis
OBJECTIVES: School-based sex education is a cornerstone of HIV prevention for adolescents who continue to bear a disproportionally high HIV burden globally. We systematically reviewed and meta-analyzed the existing evidence...
