Category Archives: Prevention

HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: A systematic review and meta-analysis

2012

Background: Methadone maintenance treatment (MMT) was implemented in China since 2004. It was initiated in 8 pilot clinics and subsequently expanded to 738 clinics by the end of 2011. Numerous...

An exploratory review of HIV prevention mass media campaigns targeting men who have sex with men

2014

BACKGROUND: Men who have sex with men (MSM) are at increased risk of HIV infection in both high- and low-income settings. Mass media campaigns have been used as a means...

Cost-effectiveness of antenatal HIV-testing: Reviewing its pharmaceutical and methodological aspects

2004

This paper reviews the pharmacoeconomic aspects of antenatal testing for HIV. HIV is a retrovirus which is transmitted among humans through sexual contact, infected blood or blood products (needle sharing...

Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: A meta-analysis

2003

Several studies have investigated whether heterozygosity for a 32-basepair deletion in the CC chemokine receptor 5 gene (CCR5-Delta32 ) affects susceptibility to perinatal HIV-1 infection, but results have been inconclusive....

Analytic review of modeling studies of ARV Based PrEP interventions reveals strong influence of drug-resistance assumptions on the population-level effectiveness

2013

BACKGROUND: Four clinical trials have shown that oral and topical pre-exposure prophylaxis (PrEP) based on tenofovir may be effective in preventing HIV transmission. The expected reduction in HIV transmission and...

Vaginal microbicides for reducing the risk of sexual acquisition of HIV infection in women: Systematic review and meta-analysis

2012

BACKGROUND: Each year more than two million people are newly infected with HIV worldwide, a majority of them through unprotected vaginal sex. More than half of new infections in adults...

Impact of antiretroviral drugs in pregnant women and their children in Africa: HIV resistance and treatment outcomes

2013

The global community has committed itself to eliminating new pediatric HIV infections by 2015 and improving maternal, newborn, and child health and survival in the context of HIV. Such objectives...

HIV vaccine preparedness studies in the non-organization for economic co-operation and development (non-OECD) countries

2009

HIV vaccine development remains an urgent priority. Vaccine preparedness studies to assess feasibility are an important precursor to HIV vaccine trials. Studies such as these have taken place in many...

Older persons’ exclusion from sexually transmitted disease risk-reduction clinical trials

2007

BACKGROUND: The incidence of HIV and AIDS is growing faster among individuals 50 and older compared to those under 40. Although the majority of clinical trials aimed at treating diseases...

HIV sexual risk-reduction interventions for youth: A review and methodological critique of randomized controlled trials

2003

The authors review and provide a methodological critique of randomized controlled studies of HIV risk reduction interventions that measured sexual risk behavior outcomes with adolescents. Studies conducted in school, community,...

Mobility and HIV in Central America and Mexico: A critical review

2012

Mobility is a key determinant of HIV/sexually transmitted infection (STI) transmission dynamics in Asia and Africa. Scant data exist regarding its dynamic impacts on HIV/STI risk in Central America and...

Preventing HIV/AIDS risk behavior among youth

2002

The purpose of this article is to evaluate the quality of published studies conducted in North America that assessed behavior change interventions to prevent HIV/AIDS among people ages 12-24 years....

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