Category Archives: Biomedical interventions
Getting youth PrEPared: Adolescent consent laws and implications for the availability of PrEP among youth in countries outside of the United States
INTRODUCTION: Youth under the age of 25 are at high risk for HIV infection. While pre-exposure prophylaxis (PrEP) has the potential to curb new infections within this population, it is...
Providing competent, comprehensive and inclusive sexual health services for men who have sex with men in low- and middle-income countries: A scoping review
Although men who have sex with men (MSM) are disproportionately affected by HIV and other sexually transmissible infections, sexual health services for MSM in low- and middle-income countries (LMIC) remain...
Taiwan guideline on oral pre-exposure prophylaxis for HIV prevention – 2018 update
Pre-exposure prophylaxis (PrEP) for prevention of human immunodeficiency virus infection is proved to be effective and has been implemented worldwide. This article introduces the guideline development and revised recommendations and...
Forming and implementing community advisory boards in low- and middle-income countries: A scoping review
BACKGROUND: Community advisory boards (CABs) have expanded beyond high-income countries (HICs) and play an increasing role in low- and middle-income country (LMIC) research. Much research has examined CABs in HICs,...
Use of an indeterminate range in HIV early infant diagnosis: A systematic review and meta-analysis
BACKGROUND: Expanded access to HIV antiretrovirals has dramatically reduced mother-to-child transmission of HIV. However, there is increasing concern around false-positive HIV test results in perinatally HIV-exposed infants but few insights...
Adjuvanted-influenza vaccination in patients infected with HIV: A systematic review and meta-analysis of immunogenicity and safety
Adjuvanted-influenza vaccination is an efficient method for enhancing the immunogenicity of influenza split-virus vaccines for preventing influenza. However, the medical community’s understanding of its performance in patients infected with HIV...
The impact, cost and cost-effectiveness of oral pre-exposure prophylaxis in sub-Saharan Africa: A scoping review of modelling contributions and way forward
INTRODUCTION: Oral pre-exposure prophylaxis (PrEP) is a new form of HIV prevention being considered for inclusion in national prevention portfolios. Many mathematical modelling studies have been undertaken that speak to...
What will it take for the global plan priority countries in sub-Saharan Africa to eliminate mother-to-child transmission of HIV?
BACKGROUND: The 2016 ‘Start Free, Stay Free, AIDS Free’ global agenda, builds on the 2011-2015 ‘Global Plan’. It prioritises 22 countries where 90% of the world’s HIV-positive pregnant women live...
Adherence to HIV post-exposure prophylaxis for children/adolescents who have been sexually assaulted: A systematic review of barriers, enablers, and interventions
Post-exposure prophylaxis (PEP) is a key intervention for preventing HIV acquisition, including following sexual assault. However, uptake and completion rates for HIV PEP are lowest following sexual assault, with only...
