Category Archives: Biomedical interventions

Educational technologies and practices for prevention of vertical HIV transmission

2018

OBJECTIVE: to assess available evidence on educational technologies and practices for prevention of vertical HIV transmission. METHOD: LILACS, PubMed, Scopus, BDENF, between April and May 2016, with the descriptors: “Vertical...

Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States

2018

BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...

Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: A systematic review and meta-analysis

2018

INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...

Economic evaluations of pre- and post-exposure prophylaxis for HIV

2019

Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...

Cost-effectiveness of front-line services (Updated 2010)

2010

Key take-home messages There is no one-size-fits-all cost-effective HIV strategy. An intervention that is found to be effective at preventing HIV infection has a good chance of being cost-effective due...

Effectiveness of female condoms for preventing HIV/AIDS and factors that impact uptake

2010

Key take-home messages The use of prophylactics in the prevention of HIV transmission has traditionally centered on the male condom. Negotiation of condom use has therefore been largely male-centric. The...

Women and HIV/HCV co-infection

2010

Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...

Effectiveness and cost-effectiveness of pre- & post-exposure prophylaxis for HIV

2010

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Psychosocial support programs for HIV-positive women who are pregnant

2011

Key take-home messages Pregnant women with HIV have distinct psychosocial needs that must be addressed. Very little research has investigated the most effective means of delivering psychosocial support to pregnant...

Female condom use for men who have sex with men

2013

Key take-home messages Men who have sex with men who have used a female condom often complain of irritation, bunching up, unpleasant texture, noise, discomfort upon insertion, lack of pleasure,...

Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)

2013

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

Gay men’s attitudes towards and perceptions of viral load and treatment as prevention

2014

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

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