Category Archives: Biomedical interventions

BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...

INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...

Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...

Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...

Key take-home messages The use of prophylactics in the prevention of HIV transmission has traditionally centered on the male condom. Negotiation of condom use has therefore been largely male-centric. The...

Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Key take-home messages Pregnant women with HIV have distinct psychosocial needs that must be addressed. Very little research has investigated the most effective means of delivering psychosocial support to pregnant...

Key take-home messages Men who have sex with men who have used a female condom often complain of irritation, bunching up, unpleasant texture, noise, discomfort upon insertion, lack of pleasure,...

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...