Category Archives: Biomedical interventions

Effects of pre-exposure prophylaxis for the prevention of HIV infection on sexual risk behavior in men who have sex with men: A systematic review and meta-analysis

2018

Background: HIV pre-exposure prophylaxis (PrEP) is effective in reducing HIV risk in men who have sex with men (MSM). However concerns remain that risk compensation in PrEP users may lead...

The impact of programs for prevention of mother-to-child transmission of HIV on health care services and systems in sub-Saharan Africa – A review

2017

Background: The global scale-up of Prevention of mother-to-child transmission (PMTCT) services is credited for a 52% worldwide decline in new HIV infections among children between 2001 and 2012. However, the...

Male partner involvement in increasing the uptake of infant antiretroviral prophylaxis/treatment in sub Saharan Africa: A systematic review and meta-analysis

2018

BACKGROUND: Infant antiretroviral prophylaxis plays an important role towards ensuring the reduction of HIV transmission from mother to child in the postpartum period. However in sub Saharan Africa (SSA), the...

Geospatial indicators of space and place: A review of multilevel studies of HIV prevention and care outcomes among young men who have sex with men in the United States

2017

Young men who have sex with men (YMSM), particularly YMSM who are racial/ethnic minorities, are disproportionately affected by the human immunodeficiency virus (HIV) epidemic in the United States. These HIV...

A meta-analysis of HIV postexposure prophylaxis among sexually assaulted patients in the United States

2018

Sexual assault (SA) is a major public health problem that leaves patients at risk for HIV. The gold standard of medical treatment for SA patients includes prophylactic treatment to prevent...

Interventions to significantly improve service uptake and retention of HIV-positive pregnant women and HIV-exposed infants along the prevention of mother-to-child transmission continuum of care: Systematic review

2018

OBJECTIVES: Despite the success of Prevention of Mother-to-Child Transmission of HIV (PMTCT) programmes, low uptake of services and poor retention pose a formidable challenge to achieving the elimination of vertical...

Tenofovir disoproxil fumarate safety for women and their infants during pregnancy and breastfeeding

2017

OBJECTIVES: Pregnant/lactating women in some sub-Saharan Africa settings are at substantial risk of HIV acquisition and could benefit from preexposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF), but safety data...

‘Men who use the Internet to seek sex with men’: Rethinking sexuality in the transnational context of HIV prevention

2016

MISM (i.e. men who use the Internet to seek sex with men) has emerged in public health literature as a population in need of HIV prevention. In this paper, we...

Retention in HIV care during pregnancy and the postpartum period in the option B+ era: A systematic review and meta-analysis of studies in Africa

2017

BACKGROUND: Under Option B+ guidelines for prevention of mother-to-child transmission of HIV (PMTCT), pregnant and breastfeeding women initiate antiretroviral therapy (ART) for lifelong use. The objectives of this study were:...

Is pre-exposure prophylaxis effective for preventing HIV infection in men who have sex with men?

2016

INTRODUCTION: Increasing rates of HIV infection remain of concern, especially for high-risk groups such as men who have sex with men. Oral pre-exposure prophylaxis has emerged as an alternative to...

Do you PrEP? A review of primary care provider knowledge of PrEP and attitudes on prescribing PrEP

2018

Oral preexposure prophylaxis (PrEP) has been proven to be a safe and effective means of preventing HIV. The purpose of our literature review was to examine primary care provider knowledge...

Effect of point-of-care diagnostics on maternal outcomes in human immunodeficiency virus-infected women: Systematic review and meta-analysis

2017

Introduction: The World Health Organization advocates for increased accessibility of HIV-related point-of-care (POC) diagnostics in settings that lack laboratory infrastructure. The aim of this study is to assess the impact...

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