Category Archives: Biomedical interventions

PrEP is an important and useful HIV prevention strategy, yet awareness remains low among at-risk populations in the United States and elsewhere in the world. As previous studies have shown...

Background: Pre-exposure prophylaxis (PrEP) is used as an HIV prevention method by people at substantial risk of HIV infection. This systematic review and meta-analysis evaluates current clinical evidence for use...

BACKGROUND: Human immunodeficiency virus (HIV) is caused by a cytopathic lentivirus. HIV without adequate treatment during pregnancy can result in maternal to child transmission (MCT) of the virus. Sequelae can...

: When combining results from all published surveys, about one in nine global study participants (10.7%) reported ever using PrEP by 2017, a significant increase since U.S. FDA approval in...

Key take-home messages There is no one-size-fits-all cost-effective HIV strategy. An intervention that is found to be effective at preventing HIV infection has a good chance of being cost-effective due...

Key take-home messages The use of prophylactics in the prevention of HIV transmission has traditionally centered on the male condom. Negotiation of condom use has therefore been largely male-centric. The...

Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Key take-home messages Pregnant women with HIV have distinct psychosocial needs that must be addressed. Very little research has investigated the most effective means of delivering psychosocial support to pregnant...

BACKGROUND: The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of...

BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard...

BACKGROUND: Risk perception has been found to be a crucial factor explaining inconsistent or non-use of HIV prevention interventions. Considerations of risk need to expand beyond risk of infection to...