Category Archives: Biomedical interventions

Does male circumcision reduce women’s risk of sexually transmitted infections, cervical cancer, and associated conditions?

2019

Background: Male circumcision (MC) is proven to substantially reduce men’s risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to...

The efficacy of post-exposure prophylaxis (PEP) for HIV

2019

Key take-home messages PEP initiated soon after exposure can reduce the risk of HIV seroconversion after occupational and non-occupational exposures, provided adherence to medications is sufficient. Evidence suggests that individuals...

The impact of location on implementation of HIV/STI prevention interventions among LGBTQ communities

2019

Key take-home messages The characteristics of a location, including segregation, community-level stigma, and infrastructural resources, may influence HIV service utilization and the HIV continuum of care among men who have...

The effect of demand-side financial incentives for increasing linkage into HIV treatment and voluntary medical male circumcision: A systematic review and meta-analysis of randomised controlled trials in low- and middle-income countries

2018

INTRODUCTION: Linkage to HIV treatment is a vital step in the cascade of HIV services and is critical to slowing down HIV transmission in countries with high HIV prevalence. Equally,...

HIV, sexually transmitted infection, and substance use continuum of care interventions among criminal justice-involved black men who have sex with men: A systematic review

2018

BACKGROUND: Because Black men who have sex with men (BMSM) experience high rates of both HIV and incarceration relative to other groups, the various stages of criminal justice involvement may...

Educational technologies and practices for prevention of vertical HIV transmission

2018

OBJECTIVE: to assess available evidence on educational technologies and practices for prevention of vertical HIV transmission. METHOD: LILACS, PubMed, Scopus, BDENF, between April and May 2016, with the descriptors: “Vertical...

Evolving models and ongoing challenges for HIV preexposure prophylaxis implementation in the United States

2018

BACKGROUND: The use of preexposure prophylaxis (PrEP) for HIV prevention was approved by the Food and Drug Administration in 2012, but delivery to at-risk persons has lagged. This critical review...

Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: A systematic review and meta-analysis

2018

INTRODUCTION: Identification and retention of HIV-exposed infants in early infant diagnosis (EID) services helps to ensure optimal health outcomes. This systematic review and meta-analysis examines the magnitude of attrition from...

Economic evaluations of pre- and post-exposure prophylaxis for HIV

2019

Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging. PrEP can be cost-effective or cost-saving...

Integration of neonatal and child health interventions with pediatric HIV interventions in global health

2018

Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...

Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review

2019

Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...

Male partner involvement in the utilization of hospital delivery services by pregnant women living with HIV in sub Saharan Africa: A systematic review and meta-analysis

2019

Objective The level of male partner involvement in hospital delivery by pregnant women living with HIV in sub Saharan Africa (SSA) is low. We conducted a systematic review and meta-analysis...

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