Efficacy and safety of oral TDF-based pre-exposure prophylaxis for men who have sex with men: A systematic review and meta-analysis
2018
Background: Pre-exposure prophylaxis (PrEP) is used as an HIV prevention method by people at substantial risk of HIV infection. This systematic review and meta-analysis evaluates current clinical evidence for use...
Congenital HIV: Prevention of maternal to child transmission
2018
BACKGROUND: Human immunodeficiency virus (HIV) is caused by a cytopathic lentivirus. HIV without adequate treatment during pregnancy can result in maternal to child transmission (MCT) of the virus. Sequelae can...
Increasing prevalence of self-reported HIV pre-exposure prophylaxis (PrEP) use in published surveys – A systematic review and meta-analysis
2018
: When combining results from all published surveys, about one in nine global study participants (10.7%) reported ever using PrEP by 2017, a significant increase since U.S. FDA approval in...
Cost-effectiveness of front-line services (Updated 2010)
2010
Key take-home messages There is no one-size-fits-all cost-effective HIV strategy. An intervention that is found to be effective at preventing HIV infection has a good chance of being cost-effective due...
Effectiveness of female condoms for preventing HIV/AIDS and factors that impact uptake
2010
Key take-home messages The use of prophylactics in the prevention of HIV transmission has traditionally centered on the male condom. Negotiation of condom use has therefore been largely male-centric. The...
Women and HIV/HCV co-infection
2010
Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...
The effect of mobility on HIV-related healthcare access and use for female sex workers: A systematic review
2018
Female sex workers (FSW) experience a high HIV burden and are often mobile. FSW access to HIV-related healthcare is essential for equitable welfare and to reduce new HIV infections. We...
Medication adherence in pregnant women with human immunodeficiency virus receiving antiretroviral therapy in sub-Saharan Africa: A systematic review
2018
BACKGROUND: The use of antiretroviral therapy (ART) is a core strategy proposed by the World Health Organization in preventing mother to child transmission (MTCT) of HIV. This systematic review aimed...
A systematic review and meta-analysis of vertical transmission route of HIV in Ethiopia
2018
BACKGROUND: The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of...
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs
2018
BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard...
Risk perception and the influence on uptake and use of biomedical prevention interventions for HIV in sub-Saharan Africa: A systematic literature review
2018
BACKGROUND: Risk perception has been found to be a crucial factor explaining inconsistent or non-use of HIV prevention interventions. Considerations of risk need to expand beyond risk of infection to...
Improving PrEP implementation through multilevel interventions: A synthesis of the literature
2018
There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...
