Category Archives: Biomedical interventions

The effect of mobility on HIV-related healthcare access and use for female sex workers: A systematic review

2018

Female sex workers (FSW) experience a high HIV burden and are often mobile. FSW access to HIV-related healthcare is essential for equitable welfare and to reduce new HIV infections. We...

Medication adherence in pregnant women with human immunodeficiency virus receiving antiretroviral therapy in sub-Saharan Africa: A systematic review

2018

BACKGROUND: The use of antiretroviral therapy (ART) is a core strategy proposed by the World Health Organization in preventing mother to child transmission (MTCT) of HIV. This systematic review aimed...

A systematic review and meta-analysis of vertical transmission route of HIV in Ethiopia

2018

BACKGROUND: The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of...

Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs

2018

BACKGROUND: Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers. Antiretroviral therapy (ART) is the standard...

Risk perception and the influence on uptake and use of biomedical prevention interventions for HIV in sub-Saharan Africa: A systematic literature review

2018

BACKGROUND: Risk perception has been found to be a crucial factor explaining inconsistent or non-use of HIV prevention interventions. Considerations of risk need to expand beyond risk of infection to...

Improving PrEP implementation through multilevel interventions: A synthesis of the literature

2018

There are many challenges to accessing PrEP and thus low uptake in the United States. This review (2007-2017) of PrEP implementation identified barriers to PrEP and interventions to match those...

A systematic review of the current status of safer conception strategies for HIV affected heterosexual couples in Sub-Saharan Africa

2018

We conducted a systematic review of safer conception strategies (SCS) for HIV-affected couples in sub-Saharan Africa to inform evidence-based safer conception interventions. Following PRISMA guidelines, we searched fifteen electronic databases...

Sexualised drug use in the United Kingdom (UK): A review of the literature

2018

BACKGROUND: Sexualised drug use (SDU) refers to the use of drugs in a sexual context. This includes ‘Chemsex’- the use of drugs (specifically crystal methamphetamine, GHB/GBL and mephedrone) before or...

HIV preexposure prophylaxis: A review

2018

Importance: About 40000 Americans and 2 million people worldwide are newly infected with HIV each year. The combination antiretroviral regimen, tenofovir disoproxil fumarate (TDF)/emtricitabine, taken as a single pill once...

The effect of human immunodeficiency virus and cytomegalovirus infection on infant responses to vaccines: A review

2018

The success of prevention of mother to child transmission programs over the last two decades has led to an increasing number of infants who are exposed to human immunodeficiency virus...

Nanotechnology and the future of condoms in the prevention of sexually transmitted infections

2018

Objective: The human immunodeficiency virus (HIV) is among the utmost destructive viruses humankind has ever faced in almost four decades. It carries with it profound socioeconomic and public health implications....

Effects of pre-exposure prophylaxis for the prevention of HIV infection on sexual risk behavior in men who have sex with men: A systematic review and meta-analysis

2018

Background: HIV pre-exposure prophylaxis (PrEP) is effective in reducing HIV risk in men who have sex with men (MSM). However concerns remain that risk compensation in PrEP users may lead...

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