Category Archives: Biomedical interventions

Starter packs versus full prescription of antiretroviral drugs for postexposure prophylaxis: A systematic review

2015

BACKGROUND: The provision of starter packs for human immunodeficiency virus postexposure prophylaxis (PEP) is practiced in many settings to facilitate rapid initiation by nonexperts and encourage adherence. However, the impact...

Barriers to successful implementation of prevention-of-mother-to-child-transmission (PMTCT) of HIV programmes in Malawi and Nigeria: A critical literature review study

2014

Mother-to-child-transmission (MTCT) of HIV still remains a significant route of new HIV infection in children in Malawi and Nigeria, despite the introduction of Prevention-of-Mother-to-Child-Transmission (PMTCT) of HIV programmes in both...

Pharmacologic management of human immunodeficiency virus wasting syndrome

2014

Pharmacologic interventions for human immunodeficiency virus (HIV) wasting have been studied since the 1990s, but the results of these interventions have been difficult to compare because the studies used different...

Choice of antiretroviral drugs for postexposure prophylaxis for children: A systematic review

2015

BACKGROUND: This systematic review aimed to assess the safety and efficacy of antiretroviral options for postexposure prophylaxis (PEP). Recognizing the limited data on the safety and efficacy of antiretroviral drugs...

Elevations in serum creatinine with tenofovir-based HIV pre-exposure prophylaxis: A meta-analysis of randomized placebo-controlled trials

2016

No abstract.

Universal voluntary HIV testing in antenatal care settings: A review of the contribution of provider-initiated testing & counselling

2012

Objective To assess the contribution of provider-initiated testing and counselling (PITC) to achieving universal testing of pregnant women and, from available data on components of PITC, assess whether PITC adoption...

What works to meet the sexual and reproductive health needs of women living with HIV/AIDS

2011

It is critical to include a sexual and reproductive health lens in HIV programming as most HIV transmission occurs through sexual intercourse. As global attention is focusing on the sexual...

HIV prevention programs with heterosexuals

2000

Objective: Efficacious HIV prevention programs designed for heterosexual adults were identified. Methods: Thirty-two programs designed with a comparison group and aimed at preventing heterosexual transmission for HIV were identified utilizing...

Experiences integrating delivery of maternal and child health services with childhood immunization programs: Systematic review update

2012

BACKGROUND: The World Health Organization and the United Nations Children’s Fund promote integration of maternal and child health (MCH) and immunization services as a strategy to strengthen immunization programs. We...

The uptake of integrated perinatal prevention of mother-to-child HIV transmission programs in low- and middle-income countries: A systematic review

2013

BACKGROUND: The objective of this review was to assess the uptake of WHO recommended integrated perinatal prevention of mother-to-child transmission (PMTCT) of HIV interventions in low- and middle-income countries. METHODS...

The evolving design and methods for trials evaluating the safety of candidate vaginal microbicides: A systematic review

2013

Vaginal preexposure prophylaxis is a promising biomedical tool for HIV prevention. Although guidelines for the clinical assessment of microbicides are available, validated markers for product safety are lacking. To inform...

Hormonal contraceptive use and female-to-male HIV transmission: A systematic review of the epidemiologic evidence

2013

OBJECTIVE: To systematically review epidemiologic evidence assessing whether hormonal contraception alters the risk of HIV transmission from an HIV-positive woman to an HIV-negative male partner. DESIGN: Systematic review. METHODS: We...

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