Category Archives: Health Systems

Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

2022

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings...

Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: A systematic review and meta-analysis

2022

Background: Abacavir is a nucleoside reverse transcriptase inhibitor recommended in paediatric HIV care. We assessed the safety and efficacy profile of abacavir used in first, second, or subsequent lines of treatment...

Economic benefits of the United States’ AIDS drug assistance program: A systematic review of cost analyses to guide research and policy priorities

2022

As part of the Ryan White HIV/AIDs Program, the federally-funded, state-administered AIDS Drug Assistance Program (ADAP) provides prescription drug medications, including antiretroviral therapy, for people with HIV (PWH) who are...

The clinical effect of point-of-care HIV diagnosis in infants: A systematic review and meta-analysis

2022

Background: Timely diagnosis and treatment of HIV is crucial in HIV-exposed infants to prevent the high rates of mortality seen during the first 2 years of life if HIV is untreated....

Evaluating the impact of the COVID-19 pandemic on accessing HIV services in South Africa: A systematic review

2022

Progress has been made towards controlling the Human Immunodeficiency Virus (HIV) epidemic in South Africa. However, the emergence of coronavirus disease 2019 (COVID-19) has disrupted access to health care. This...

HIV-specific patient-reported outcome measures: A systematic review of [sychometric properties

2022

BACKGROUND: The management of people living with HIV/AIDS (PLWHA) is multidimensional and complex. Using patient-reported outcome measures (PROMs) has been increasingly recognized to be the key factor for providing patient-centered...

Rethinking mental health wellness among adolescents living with HIV in the African context: An integrative review of mental wellness components

2022

OBJECTIVE: Adolescents living with HIV (ALHIV) are considered to be at heightened risk for developing mental health problems in comparison to their peers due to the burden of living with...

Provision of HIV pre-exposure prophylaxis to female patients seeking family planning services in the United States

2022

OBJECTIVE: We conducted a scoping review to assess barriers to and facilitators of integrating HIV pre-exposure prophylaxis (PrEP) and family planning (FP) at the patient, provider, and implementation levels, and...

Using the meaningful involvement of people living with HIV/AIDS (MIPA) framework to assess the engagement of sexual minority men of color in the US HIV response: A literature review

2022

Black and Latino sexual minority men (SMM) continue to be disproportionately impacted by HIV. We utilized eight components of the Meaningful Involvement of People Living with HIV/AIDS (MIPA) framework to...

Ethical HIV research with transgender and non-binary communities in the United States

2022

INTRODUCTION: Because transgender individuals experience disproportionately high rates of HIV infection, this population is an increasing focus of epidemiological and implementation science research to combat the epidemic. However, study participants,...

Same-day and rapid initiation of antiretroviral therapy in people living with HIV in Asia. How far have we come?

2022

Human immunodeficiency virus (HIV) continues to be a major public health issue, and the effectiveness of HIV prevention, diagnosis, treatment, and care varies, particularly in the Asia-Pacific region. The rapid...

Factors associated with catastrophic health expenditure in sub-Saharan Africa: A systematic review

2022

OBJECTIVE: A non-negligible proportion of sub-Saharan African (SSA) households experience catastrophic costs accessing healthcare. This study aimed to systematically review the existing evidence to identify factors associated with catastrophic health...

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