Category Archives: Health Systems

A systematic review and meta-analysis of psychosocial interventions to reduce drug and sexual blood borne virus risk behaviours among people who inject drugs

2017

Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis...

HIV testing in men who have sex with men: A follow-up review of the qualitative literature since 2010

2017

The landscape of HIV testing has changed significantly in recent years following the rise in importance of the ‘treatment as prevention’ strategy and advancements in new HIV testing and prevention...

Cooccurrences of putative endogenous retrovirus-associated diseases

2017

At least 8% of the human genome is composed of endogenous retrovirus (ERV) sequences. ERVs play a role in placental morphogenesis and can sometimes protect the host against exogenous viruses....

Impact of telemonitoring approaches on integrated HIV and TB diagnosis and treatment interventions in sub-Saharan Africa: A scoping review

2017

Background: This paper explores telemonitoring/mhealth approaches as a promising real time and contextual strategy in overhauling HIV and TB interventions quality access and uptake, retention,adherence and coverage impact in endemic...

The potential cost-effectiveness of HIV vaccines: A systematic review

2017

OBJECTIVE: The aim of this paper was to review and compare HIV vaccine cost-effectiveness analyses and describe the effects of uncertainty in model, methodology, and parameterization. METHODS: We systematically searched...

Integrated opioid substitution therapy and HIV care: A qualitative systematic review and synthesis of client and provider experiences

2017

People who use drugs in many contexts have limited access to opioid substitution therapy and HIV care. Service integration is one strategy identified to support increased access. We reviewed and...

Enhancing public health HIV interventions: A qualitative meta-synthesis and systematic review of studies to improve linkage to care, adherence, and retention

2017

Although HIV services are expanding, few have reached the scale necessary to support universal viral suppression of individuals living with HIV. The purpose of this systematic review was to summarize...

The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: Systematic and realist reviews and intervention development

2017

BACKGROUND: Men who have sex with men (MSM) experience significant inequalities in health and well-being. They are the group in the UK at the highest risk of acquiring a human...

Can trained lay providers perform HIV testing services? A review of national HIV testing policies

2017

BACKGROUND: Only an estimated 54% of people living with HIV are aware of their status. Despite progress scaling up HIV testing services (HTS), a testing gap remains. Delivery of HTS...

Interferon-free therapies for patients with chronic hepatitis C genotype 3 infection: A systematic review

2016

Treatment of hepatitis C virus (HCV) infection with genotype 3 remains a challenge. The HCV elimination rate with direct-acting antivirals (DAAs) is lower than the values reported for other HCV...

Values and preferences on the use of oral pre-exposure prophylaxis (PrEP) for HIV prevention among multiple populations: A systematic review of the literature

2017

Daily oral pre-exposure prophylaxis (PrEP) is the use of antiretroviral drugs by HIV-negative people to prevent HIV infection. WHO released new guidelines in 2015 recommending PrEP for all populations at...

An integrative review of the efficacy of motivational interviewing in HIV management

2017

OBJECTIVE: The purpose of this integrative review is to examine the use of motivational interviewing (MI) to improve health outcomes in persons living with HIV (PLWH). METHODS: We reviewed the...

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