Category Archives: Health Systems
Possible benefits of providing safe supply of substances to people who use drugs during public health emergencies such as the COVID-19 pandemic
Key take-home messages Safe supply is an approach that focuses on saving lives by prescribing pharmaceutical grade substances such as opioids and stimulants to individuals at risk of overdose and...
The costs of home-based HIV testing and counselling in sub-Saharan Africa and its association with testing yield: A literature review
More than 14.5 of the 36.7 million people living with HIV globally do not know their HIV status, making comprehensive testing interventions a critical step in ending the HIV/AIDS epidemic....
Different transmission routes and the risk of advanced HIV disease: A systematic review and network meta-analysis of observational studies
Background: A substantial proportion of people living with HIV (PLHIV) present for care with advanced HIV disease (AHD), which may result in difficulty reaching the “90-90-90” target to end AIDS...
Service delivery interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review
BACKGROUND: Voluntary medical male circumcision (VMMC) remains an essential component of combination HIV prevention services, particularly in priority countries in sub-Saharan Africa. As VMMC programs seek to maximize impact and...
Meta-analysis of average costs of HIV testing and counselling and voluntary medical male circumcision across thirteen countries
Objective: Explore facility-level average costs per client of HIV testing and counselling (HTC) and voluntary medical male circumcision (VMMC) services in 13 countries.Methods: Through a literature search we identified studies...
Cost of differentiated HIV antiretroviral therapy delivery strategies in sub-Saharan Africa: A systematic review
BACKGROUND: Efficient and scalable models for HIV treatment are needed to maximize health outcomes with available resources. By adapting services to client needs, differentiated antiretroviral therapy (DART) has the potential...
Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017
This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...
ART adherence clubs in the Western Cape of South Africa: What does the sustainability framework tell us? A scoping literature review
INTRODUCTION: In 2007, the antiretroviral therapy (ART) adherence club (AC) model was introduced to South Africa to combat some of the health system barriers to ART delivery, such as staff...
Economic compensation interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review and meta-analysis
BACKGROUND: Economic compensation interventions may help support higher voluntary medical male circumcision (VMMC) coverage in priority sub-Saharan African countries. To inform World Health Organization guidelines, we conducted a systematic review...
What will it take for the global plan priority countries in sub-Saharan Africa to eliminate mother-to-child transmission of HIV?
BACKGROUND: The 2016 ‘Start Free, Stay Free, AIDS Free’ global agenda, builds on the 2011-2015 ‘Global Plan’. It prioritises 22 countries where 90% of the world’s HIV-positive pregnant women live...
