Category Archives: Health Systems
Barriers and facilitators of rendering HIV services by community health workers in sub-Saharan Africa: A meta-synthesis
OBJECTIVES: To synthesise qualitative studies that address the barriers to and facilitators of providing HIV services by community health workers (CHWs) in sub-Saharan Africa (SSA). DESIGN: This meta-synthesis was guided...
Association between adherence to antiretroviral therapy and place of residence among adult HIV infected patients in Ethiopia: A systematic review and meta-analysis
BACKGROUND: According to the World Health Organization, optimal adherence to Antiretroviral Therapy (ART) improves quality of life. Patients who use ART have varying characteristics in terms of where they live....
The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer
Cervical cancer is a public health problem and has devastating effects in low-to-middle-income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by the human papillomavirus (HPV) is the...
Same-day antiretroviral therapy initiation for people living with HIV who have tuberculosis symptoms: A systematic review
Objectives Tuberculosis symptoms are very common among people living with HIV (PLHIV) initiating antiretroviral therapy (ART), are not specific for tuberculosis disease and may result in delayed ART start. The...
Experience of chronic noncommunicable disease in people living with HIV: A systematic review and meta-aggregation of qualitative studies
BACKGROUND: An increasing number of people living with HIV (PLWH) have had chronic noncommunicable diseases (NCDs) over the last 5 years. However, robust evidence regarding the perception and challenges of...
HIV-proteins-associated CNS neurotoxicity, their mediators, and alternative treatments
Human immunodeficiency virus (HIV)-infected people’s livelihoods are gradually being prolonged with the use of combined antiretroviral therapy (ART). Conversely, despite viral suppression by ART, the symptoms of HIV-associated neurocognitive disorder...
TLR-agonist mediated enhancement of antibody-dependent effector functions as strategy for an HIV-1 cure
BACKGROUND: The current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it...
Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: A systematic integrative review
OBJECTIVES: People who inject drugs (PWID) experience a high burden of injection drug use-related infectious disease and challenges in accessing adequate care. This study sought to identify programmes and services...
HIV care outcomes among transgender persons with HIV infection in the united states: A systematic review and meta-analysis, 2006–2021
Objectives: HIV prevalence is an estimated 14% among transgender women (TW) and 3% among transgender men (TM). HIV care is vital for viral suppression but is hindered by transphobia and HIV...
Pharmacy-based interventions to increase use of HIV pre-exposure prophylaxis in the United States: A scoping review
HIV pre-exposure prophylaxis (PrEP) remains underutilized in the U.S. Since greater than 85% of PrEP prescriptions are filled at commercial pharmacies, pharmacists are uniquely positioned to increase PrEP use. This...
