Category Archives: Delivery arrangements
How care is organized
An exploration of group-based HIV/AIDS treatment and care models in Sub-Saharan Africa using a realist evaluation (Intervention-Context-Actor-Mechanism-Outcome) heuristic tool: A systematic review
INTRODUCTION: It is increasingly acknowledged that differentiated care models hold potential to manage large volumes of patients on antiretroviral therapy (ART). Various group-based models of ART service delivery aimed at...
Specification of implementation interventions to address the cascade of HIV care and treatment in resource-limited settings: A systematic review
BACKGROUND: The global response to HIV has started over 18 million persons on life-saving antiretroviral therapy (ART)-the vast majority in low- and middle-income countries (LMIC)-yet substantial gaps remain: up to...
Linkage-to-care methods and rates in U.S. emergency department-based HIV testing programs: A systematic literature review brief report
BACKGROUND: An increasing number of U.S. emergency departments (EDs) have implemented ED-based HIV testing programs since the Centers for Disease Control and Prevention issued revised HIV testing recommendations for clinical...
The peer and non-peer: The potential of risk management for HIV prevention in contexts of prostitution
Sex workers have been the protagonists and focus of HIV prevention campaigns and research since the late 1980s in Brazil. Through a review of national and international literature, combined with...
Efficacy and tolerability of tenofovir disoproxil fumarate based regimen as compared to zidovudine based regimens: A systematic review and meta-analysis
BACKGROUND: Although tenofovir (TDF)/emtricitabine (FTC)/efavirenz (EFV) and zidovudine (ZDV)/lamivudine (3TC)/efavirenz (EFV) are used as preferred first line regimen, their head-to-head comparison in terms of their efficacy and tolerability was limited....
Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades
BACKGROUND: In 2014, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and partners set the ’90-90-90 targets’; aiming to diagnose 90% of all HIV positive people, provide antiretroviral...
Mapping evidence of interventions and strategies to bridge the gap in the implementation of the prevention of mother-to-child transmission of HIV programme policy in sub-Saharan countries: A scoping review
BACKGROUND: Prevention of mother-to-child transmission (PMTCT) of HIV is a life-saving public health intervention. Sub-Saharan African (SSA) countries have made significant progress in the programme, but little is known about...
A review of the efficacy and safety of genvoya(R) (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) in the management of HIV-1 infection
INTRODUCTION: This review evaluates the efficacy and safety of Genvoya(R) (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide [EVG/c/TAF/FTC]), a single-tablet regimen used for the management of HIV-1 infection. Phase II and...
HIV screening in pregnant women: A systematic review of cost-effectiveness studies
INTRODUCTION: Vertical transmission represents the major route of HIV infection for children. However, the preventive interventions available are extremely effective. This review summarizes evidence regarding the cost-effectiveness of mother-to-child-transmission preventive...
Non-communicable diseases and HIV care and treatment: Models of integrated service delivery
OBJECTIVES: Non-communicable diseases (NCD) are a growing cause of morbidity in low-income countries including in people living with human immunodeficiency virus (HIV). Integration of NCD and HIV services can build...
Examining the effects of HIV self-testing compared to standard HIV testing services: A systematic review and meta-analysis
INTRODUCTION: HIV self-testing (HIVST) is a discreet and convenient way to reach people with HIV who do not know their status, including many who may not otherwise test. To inform...
