Category Archives: Testing
Examining the use of HIV self-testing to support PrEP delivery: A systematic literature review
PURPOSE OF REVIEW: HIV self-testing (HIVST) has the potential to expand access to and uptake of HIV pre-exposure prophylaxis (PrEP) delivery. We conducted a systematic literature review to understand the...
The effect of universal voluntary HIV counseling and testing on epidemiological, behavioral, and psychosocial outcomes: An umbrella review of systematic reviews and meta-analyses
BACKGROUND: Despite progress in reducing global HIV-related mortality, the decrease in the rate of HIV incidence remains slow. As such, HIV testing remains crucial to the prevention of HIV and...
Early diagnosis, vertical transmission of HIV and its associated factors among exposed infants after implementation of the Option B+ regime in Ethiopia: A systematic review and meta-analysis
Introduction Despite scaling up programmes to prevent vertical transmission of human immunodeficiency virus (HIV), over 400 children are infected every day globally. Guidelines recommend that all HIV-exposed infants should be...
Acceptability assessment in HIV prevention and treatment intervention and service delivery research: A systematic review and qualitative analysis
We reviewed the literature on the assessment of acceptability of HIV prevention and treatment interventions and service delivery strategies. Following PRISMA guidelines, we screened 601 studies published from 2015 to...
Evidence and implication of interventions across various socioecological levels to address HIV testing uptake among men who have sex with men in the United States: A systematic review
OBJECTIVES: Strengthening HIV testing uptake is critical to curtail the HIV epidemics among men who have sex with men in the United States. Despite the implementation of various interventions to...
Viral blood-borne infections testing and linkage to care cascade among persons who experience homelessness in the United States: A systematic review and meta-analysis
BACKGROUND: Persons who experience homelessness remain at increased risk for three viral blood-borne infections: human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). We assessed the...
Interventions addressing the adolescent HIV continuum of care in South Africa: A systematic review and modified Delphi analysis
INTRODUCTION: Compared with adults, adolescents in South Africa have larger gaps at each step of the HIV continuum of care resulting in low levels of viral suppression. METHODS: We conducted...
Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis
Background: WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with AlereLAM in HIV-positive inpatients only if screening criteria are met. We assessed the performance of WHO screening criteria and alternative screening tests/strategies...
Voluntary counseling and testing, antiretroviral therapy access, and HIV-related stigma: Global progress and challenges
To date, about 37 million people are living with the human immunodeficiency virus (HIV) and an estimated 680,000 people have died from acquired immune deficiency syndrome (AIDS) related illnesses globally....
Clinical decision support systems to guide healthcare providers on HIV testing
Objective: To understand the impact of clinical decision support systems (CDSSs) on improving HIV testing and diagnosis. Design: An original global systematic review (PROSPERO Number: CRD42020175576) of peer-reviewed articles reporting on electronic...
Incentive-based human immunodeficiency virus screening in low- and middle-income countries: A systematic review
BACKGROUND: The majority of new human immunodeficiency virus (HIV) infections that occur worldwide are in sub-Saharan Africa. While recent gains have been made in many low- and middle-income countries (LMICs),...
