SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence and global trends of polypharmacy among people living with HIV: A systematic review and meta-analysis

2022

Background: There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients. Methods: We conducted...

Applying behavioural insights to HIV prevention and management: A scoping review

2022

PURPOSE OF REVIEW: This scoping review summarises the literature on HIV prevention and management interventions utilizing behavioural economic principles encapsulated in the MINDSPACE framework. RECENT FINDINGS: MINDSPACE is an acronym...

HIV sero-status disclosure and associated factors among HIV positive women in East Africa: Systematic review and meta-analysis. Implications for prevention of mother-to-child HIV transmission

2022

BACKGROUND: Women’s HIV-positive disclosure plays a pivotal role to achieve the goal of preventing mother-to-child transmission (PMTCT) among pregnant women in particular. Although several primary studies were conducted in the...

Prevalence of hepatotoxicity among HIV-infected patients in Ethiopia: A systematic review and meta-analysis

2022

Background: Globally, the human immunodeficiency virus has been recognized as a major public health concern. The direct toxicity of antiretroviral medicines or their active metabolites causes liver cell destruction by different...

Antiretroviral therapy management in adults with HIV during ICU admission

2022

The extended lifespan of people living with human immunodeficiency (HIV) and acquired immune deficiency syndrome (AIDS) (PLWHA) has increased the potential for ICU admissions unrelated to HIV infection. The objective...

Under-nutrition and associated factors among children infected with human immunodeficiency virus in sub-Saharan Africa: A systematic review and meta-analysis

2022

Background In the developing world, such as the sub-Saharan African region, HIV/AIDS has worsened the impact of under-nutrition in children. HIV infected children are highly vulnerable to under-nutrition. Therefore, the...

Incidence of impaired kidney function among people with HIV: A systematic review and meta-analysis

2022

Background: In the era of combination antiretroviral therapy (ART), the incidence, manifestations and severity of kidney diseases have dramatically changed in people living with HIV (PLWH). Little is known about the...

Interventions to improve early retention of patients in antiretroviral therapy programmes in sub-Saharan Africa: A systematic review

2022

BACKGROUND: Several interventions to improve long term retention (12 months and above) on treatment have been rigorously evaluated in Sub-Saharan Africa (SSA). However, research on interventions to improve retention of...

Factors associated with viral suppression among cisgender women living with human immunodeficiency virus in the United States: An integrative review

2022

Introduction: Women account for 23% of new human immunodeficiency virus diagnoses in the United States, yet remain understudied. Adherence to antiretroviral therapy and consequent viral suppression are keys to preventing human...

Barriers and facilitators to acceptability of the female condom in low- and middle-income countries: A systematic review

2022

BACKGROUND: Sexually transmitted infections, including HIV, remain a significant public health challenge for low- and middle-income countries, and about 111 million unintended pregnancies occur in these countries annually. The female...

A review of sexual transmitted infection rates among sexually assaulted patients that present for care

2022

BACKGROUND: Patients who experience sexual assault are at risk of adverse health outcomes including sexually transmitted infections (STI) and often present to various healthcare centers for post-assault care. Unfortunately, there...

The effect of perinatal HIV and antiretroviral therapy on vascular structure and function in young people: A systematic review and meta-analysis

2022

Background and aims Perinatal HIV infection (PHIV) and prolonged use of antiretroviral therapy (ART) may increase the likelihood of developing subclinical vascular dysfunction at an early age. We conducted a...

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