SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Pharmacokinetics of antiretroviral drugs in older people living with HIV: A systematic review

2023

Background and objective: The life expectancy of people living with HIV (PLWHIV) has significantly improved in recent decades, mostly due to antiretroviral (ARV) therapy. Aging can affect the pharmacokinetics of drugs...

The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: A systematic review and meta-analysis

2023

Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis...

HPV infection profiles among people living with HIV and HPV vaccine acceptance among individuals with different HIV infection statuses in China: A systematic review and meta-analysis

2023

To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in...

Statistical methods applied for the assessment of the HIV cascade and continuum of care: A systematic scoping review

2023

OBJECTIVES: This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of...

Determining the screening frequency for sexually transmitted infections for people who use HIV pre-exposure prophylaxis: A systematic review and meta-analysis

2023

Background: Although the World Health Organization (WHO) recommends ‘frequent’ screening of sexually transmitted infections (STI) for people who use pre-exposure prophylaxis (PrEP) for HIV, there is no evidence for optimal frequency....

Performance of cardiovascular risk prediction models among people living with HIV: A systematic review and meta-analysis

2023

Importance  Extant data on the performance of cardiovascular disease (CVD) risk score models in people living with HIV have not been synthesized. Objective  To synthesize available data on the performance of the...

Immunogenicity, effectiveness and safety of SARS-CoV-2 vaccination in people living with HIV: A systematic review and meta-analysis

2023

Objectives: People living with HIV (PLWH) experience a greater risk of morbidity and mortality following COVID-19 infection, and poorer immunological responses to several vaccines. We explored existing evidence regarding the immunogenicity,...

Characteristics of psychosocial interventions to improve ART adherence in people living with HIV: A systematic review

2023

The HIV/AIDS pandemic continues to be a significant global public health crisis. The main HIV/AIDS treatment is the antiretroviral therapy (ART), which is highly effective but depends on the patient’s...

Performance of HIV infection prediction models in men who have sex with men: A systematic review and meta-analysis

2023

Effective ways to identify and predict men who have sex with men (MSM) at substantial risk for HIV is a global priority. HIV risk assessment tools can improve individual risk...

Pharmacotherapeutic interventions in people living with HIV undergoing solid organ transplantation: A scoping review

2023

The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug-drug interactions. Although various strategies...

Undetectable=Untransmittable=Universal Access (U=U=U): Transforming a foundational, community-led HIV/AIDS health informational advocacy campaign into a global HIV/AIDS health equity strategy and policy priority

2023

BACKGROUND: Undetectable=Untransmittable (U=U) first emerged in 2016 as a health information campaign to promote rigorous scientific evidence that people living with HIV (PLHIV) on effective treatment who have reached an...

A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment

2023

Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir and eradicating the virus are urgently needed....

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