SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparison of the efficacy and safety of a doravirine-based, three-drug regimen in treatment-naive HIV-1 positive adults: A bayesian network meta-analysis

2022

Introduction: Extensive use of antiretroviral therapy has remarkably improved the survival rates of people living with HIV. Doravirine (DOR) is a newly-approved antiretroviral belonging to the class of non-nucleoside reverse...

Impact of antiretroviral therapy on oral health among children living with HIV: A systematic review and meta-analysis

2022

Oral health is an integral component of general health and well-being but might be undermined among children living with HIV (CLWH) due to the condition itself or the antiretroviral therapy...

The global burden of cognitive impairment in people living with HIV: A systematic review and meta-analysis

2022

Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for...

Psychosocial interventions for depression delivered by non-mental health specialists to people living with HIV/AIDS in low- and middle-income countries: A systematic review

2022

Background: Depression commonly co-exists with human immunodeficiency virus (HIV), but in low- and middle-income countries (LMICs), where the HIV burden is greatest, mental health resources are limited. These settings may benefit...

A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV

2022

Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...

Risk of myocardial infarction in HIV patients: A systematic review

2022

Human immunodeficiency virus (HIV) is a retrovirus that is associated with mortality in the final stage. The advancement of antiretroviral therapy (ART) improved the life expectancy of patients with HIV....

Effectiveness and safety of statins on outcomes in patients with HIV infection: A systematic review and meta-analysis

2022

Statins are hypolipidaemic in human immunodeficiency virus (HIV) positive individuals. However, their effect on all-cause mortality and rate of discontinuation is unclear. We conducted a systematic review to evaluate the...

A systematic review and meta-analysis of the catastrophic costs incurred by tuberculosis patients

2022

One of the strategies of the World Health Organization End Tuberculosis (TB) was to reduce the catastrophic costs incurred by TB-affected families to 0% by 2020.Catastrophic cost is defined by...

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

2022

The incidence rates of sexually transmitted infections (STIs), including the four major curable STIs – chlamydia, gonorrhea, trichomoniasis and, syphilis – continue to increase globally, causing medical cost burden and...

Condomless sex with partners and clients among female sex workers in Iran: A systematic review and meta-analysis

2022

Condomless sex is the most proximal risk for HIV acquisition among female sex workers (FSWs). We performed a systematic review and meta-analysis to summarize the evidence for the prevalence of...

How do geriatricians feel about managing older people living with HIV? A scoping review

2022

Purpose: The proportion of people living with HIV being older adults is increasing and due to high rates of multimorbidity and frailty within this group geriatricians are well placed to contribute...

Interventions and best practices to address increasing rates of syphilis transmission

2022

Key take-home message Infectious and congenital syphilis rates have seen a sharp growth in Canada since 2016. The COVID-19 pandemic impact on syphilis rates is undetermined: some studies have shown...

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