SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The effect of antiretroviral therapy (HAART) on the periodontal conditions of patients with HIV-infection: A systematic review and meta-analysis

2022

AIM: To assess any differences (1) in the prevalence of periodontitis and necrotizing periodontal diseases, specifically necrotizing gingivitis (NG) and necrotizing periodontitis (NP) between HIV patients receiving antiretroviral therapy (HAART)...

Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A systematic review and meta-analysis

2022

BACKGROUND: Cryptococcal meningitis (CM) is a leading cause of adult meningitis in countries with a high burden of HIV. It has remained a significant cause of morbidity and mortality in...

Pediatrics HIV-positive status disclosure and its predictors in Ethiopia: A systematic review and meta-analysis

2022

INTRODUCTION: HIV-positive status disclosure for children is challenging for family members, guardians, and healthcare professionals. Disclosure is very challenging, particularly for children, yet no systematic synthesis of evidence accurately measures...

Digital directly observed therapy to monitor adherence to medications: A scoping review

2022

Background: Technology-based directly observed therapy (DOT) is more cost-effective and efficient compared with in-person monitoring visits for medication adherence. While some evidence shows these technologies are feasible and acceptable, there...

The applications of machine learning in HIV neutralizing antibodies research—A systematic review

2022

Machine learning algorithms play an essential role in bioinformatics and allow exploring the vast and noisy biological data in unrivaled ways. This paper is a systematic review of the applications...

LGBTQ+ loss and grief in a cis-heteronormative pandemic: A qualitative evidence synthesis of the COVID-19 literature

2022

LGBTQ+ people are no stranger to loss and grief, particularly during times of pandemic such as the 1980s–90s HIV/AIDS pandemic and now, the COVID-19 pandemic. Current COVID-19 loss and grief...

Curable sexually transmitted infections among women with HIV in sub-Saharan Africa: Systematic review and meta-analysis

2022

OBJECTIVES: Sexually transmitted infections (STIs) cause significant morbidity among women with HIV and increase HIV transmission. We estimated the prevalence of four STIs among women with HIV in sub-Saharan Africa...

Tuberculosis screening among HIV-positive inpatients: A systematic review and individual participant data meta-analysis

2022

Background: Since 2011, WHO has recommended that HIV-positive inpatients be routinely screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened positive, receive a molecular WHO-recommended rapid diagnostic test...

Impact of supervised aerobic exercise on clinical physiological and mental parameters of people living with HIV: A systematic review and meta-analyses of randomized controlled trials

2022

Background: The benefits derived from supervised aerobic exercise in people living with human immunofeficiency virus- HIV (PLWH) have not yet been clearly identified.Objective: To evaluate the impact of supervised aerobic exercise on...

Interventions to improve treatment outcomes among adolescents on antiretroviral therapy with unsuppressed viral Loads: A systematic review

2022

Adolescents living with HIV (ALHIV) face unique developmental challenges that increase the risk of unsuppressed viral loads. Current reviews present a need for proven interventions to improve viral suppression among...

Engaging young Black males in sexual and reproductive health care: A review of the literature

2022

Young Black males (YBM) ages 18 to 24 years are more at risk of contracting sexually transmitted infections (STIs) and have a substantially greater need for sexual reproductive health (SRH)...

Viral blood-borne infections testing and linkage to care cascade among persons who experience homelessness in the United States: A systematic review and meta-analysis

2022

BACKGROUND: Persons who experience homelessness remain at increased risk for three viral blood-borne infections: human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). We assessed the...

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