SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Mixed study systematic review and meta-analysis of sexuality and sexual rehabilitation in LGBTQI+ adults living with chronic disease

2022

OBJECTIVE: To systematically review how sexuality is experienced by lesbian, gay, bisexual, transgender, queer or questioning, intersex plus (other gender identifies and sexual orientations) (LGBTQI+) persons living with chronic disease....

Interventions to increase the uptake and continuation of pre-exposure prophylaxis (PrEP) by adolescent girls and young women at high risk of HIV in low-income and middle-income countries: A scoping review

2022

INTRODUCTION: Effective strategies to increase pre-exposure prophylaxis (PrEP) uptake and continuation among adolescent girls and young women (AGYW) who engage in sex work or transactional sex are sparsely reported. We...

The current challenges affecting the quality of care of HIV/AIDS in the Middle East: Perspectives from local experts and future directions

2022

OBJECTIVE: This report aimed to reflect the experts’ views regarding the challenges affecting the quality of care for people living with HIV in the Middle East. Besides, we integrated experts’...

Differentiating the incidence and burden of HIV by age among women who sell sex: A systematic review and meta-analysis

2022

Introduction: Young women who sell sex (YWSS) are at heightened risk of HIV acquisition and transmission and are among the least engaged in HIV services. There is insufficient epidemiologic evidence characterizing...

Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression

2022

Despite significant advances in the treatment and care of people with HIV (PWH), several challenges remain in our understanding of disease pathogenesis to improve patient care. HIV infection can modify...

Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes

2022

Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is...

The Italian PrEPventHIV challenge: A scoping systematic review on HIV pre-exposure prophylaxis monitoring in Italy

2022

BACKGROUND AND AIM: In Italy, pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) was authorized for HIV prevention in 2017. This scoping systematic review summarizes current evidence on...

A systematic review exploring racial disparities, social determinants of health, and sexually transmitted infections in Black women

2022

OBJECTIVE: To explore and describe racial disparities, the role of social determinants of health, and individual risk behaviors among Black women as related to sexual health and/or sexually transmitted infections...

Detection of HIV virologic failure and switch to second-line therapy: A systematic review and meta-analysis of data from sub-Saharan Africa

2022

BACKGROUND: The late recognition of virologic failure (VF) places persons with HIV in Sub-Saharan Africa at risk for HIV transmission, disease progression, and death. We conducted a systematic review and...

A review of internet-based testing services for HIV and sexually transmitted infections (STIs)

2022

Key take-home messages The integration of digital technologies into HIV and STI testing is becoming more prevalent, and appears to influence testing behaviours. Three models offering online HIV/STI testing that...

Perceived stigma and its association with gender and disclosure status among people living with HIV/AIDS and attending antiretroviral therapy clinics in Ethiopia: A systematic review and meta-analysis

2022

BACKGROUND: The psychological experience of being rejected, blamed, and ashamed in relation to a recognized medical disease is known as perceived stigma. It has a close connection to psychological health...

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

2022

BACKGROUND: Transmission models provide complementary evidence to clinical trials about the potential population-level incidence reduction attributable to ART (ART prevention impact). Different modelling assumptions about risk heterogeneity may influence projected...

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