SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effectiveness of digital health interventions on antiretroviral therapy adherence among people living with HIV in India: A systematic review with an RCT-only meta-analysis

2026

The widespread use of combination antiretroviral therapy has transformed HIV infection into a chronic condition, with life expectancy of people with HIV (PWH) approaching that of the general population when...

Efficacy and safety of long-acting lenacapavir for HIV treatment and prevention: A systematic review of randomized trials

2026

Background: Lenacapavir is a first-in-class, long-acting HIV-1 capsid inhibitor enabling treatment and prevention with reduced reliance on daily oral adherence. Evidence from randomized trials across indications remains fragmented. We systematically...

Culturally competent HIV prevention for African, Caribbean, and Black communities and Indigenous Peoples

2026

Key take-home messages Developing culturally sensitive approaches and materials helps ensure HIV prevention interventions are relevant, acceptable, and responsive to the needs of the intended population groups. Close collaboration with...

Burden and clinical impact of ‘neglected’ transfusion-transmitted infections in Cameroon: A systematic review and meta-analysis

2026

Background Blood supply is a public health challenge in African countries. In Cameroon, blood selection guidelines focus on four viral and bacterial pathogens (HIV, hepatitis B and C viruses, Treponema pallidum)...

Assessing the state of published HIV research concerning sexual minority women: A global English language scoping review

2026

PURPOSE: We conducted a scoping review to map peer-reviewed literature on HIV research concerning sexual minority women (SMW). METHODS: Following guidance from Arksey and O’Malley’s framework and the Preferred Reporting...

Success rate of dental implants in HIV patients: An overview of systematic reviews

2026

AIMS: To identify whether individuals with positive serology for HIV have a higher risk of losing the dental implant for this treatment. METHODS AND RESULTS: This study was conducted according...

Age-specific distribution of cervical precancer and cancer among women living with HIV across seven countries: A systematic review and an individual patient data meta-analysis

2026

Background Women living with HIV have an elevated risk for cervical cancer, present earlier, and have more recurrent human papillomavirus (HPV) infections compared with women without HIV. To update WHO recommendations...

Virus-directed CAR immunotherapies for chronic HBV and HIV: A systematic synthesis of preclinical and early clinical evidences

2026

BACKGROUND: Chronic hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections are among the most important global health issues. Virus-directed CAR-T and CAR-NK are promising strategies capable of targeting...

Understanding the implementation of patient navigation for adults living with HIV: A scoping review of components, equity considerations and lessons learned

2026

Background People living with HIV navigate complex medical and social challenges that impact engagement in care, including stigma, poverty and systemic inequities. Patient navigation has emerged as a promising approach...

Cause of death and risk of death for people living with HIV admitted to hospital: A systematic review and meta-analysis

2026

Introduction Despite increasing access to HIV treatment and care, HIV-associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living...

The reasons of late diagnosis in patients with HIV/AIDS: A meta-synthesis

2026

PURPOSE: To comprehensively integrate qualitative findings on the reasons for late diagnosis in HIV/AIDS patients and to encourage timely clinic consultations for advisory purposes. METHODS: A qualitative systematic review utilizing...

Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability

2026

Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...

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