SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Defining HIV pre-exposure prophylaxis (PrEP) persistence: A scoping review

2026

INTRODUCTION: When assessing the effectiveness of pre-exposure prophylaxis (PrEP) programmes, interventions, or modalities, it is important to understand patterns of PrEP use. Continued use of PrEP is frequently referred to...

Organization and integration of care in the HIV-non-communicable disease syndemic: A rapid scoping review

2026

Advances in antiretroviral therapy have transformed infection with HIV into a manageable chronic disease, increasing the survival of people living with HIV, who are also undergoing a demographic aging process...

Factors associated with immunological non-response in HIV patients receiving antiretroviral therapy in Southeast Asia: A systematic review

2026

Objective This systematic review summarizes factors associated with immunological non-response (INR) among people with HIV on antiretroviral therapy (ART) in Southeast Asia. Methods We conducted a systematic search of PubMed,...

The mental health of adults living with HIV in sub-Saharan Africa: Interventions along the HIV care continuum—A systematic review

2026

Although the relationship between HIV and mental health is well-established, limited research has focused on the available interventions for adults living with HIV (ALWH), particularly those in sub-Saharan Africa (SSA)...

Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials

2026

Background: HIV-associated lipodystrophy leads to visceral fat accumulation, metabolic complications, body image concerns, medication non-adherence, and increased cardiovascular risks. We thought to assess the effects of Tesamorelin, a synthetic growth hormone-releasing...

A scoping review of the methods, content, and populations of rural LGBTQ health research since the new millennium

2026

INTRODUCTION: This scoping review mapped the population characteristics, methodologies, content, and publishing trends of primary research focused on rural LGBTQ individuals since the year 2000. METHODS: We conducted a search...

Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis

2026

Background Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunodeficiency virus. However, certain situations hinder female sex workers...

Prevalence of chronic kidney disease and associated factors among adult HIV patients in Africa: A systematic review and meta-analysis

2026

Introduction: A number of individual studies in Africa reporting the prevalence of chronic kidney disease (CKD) among people living with HIV are becoming more common. This analysis aims to combine...

Mpox clinical outcomes in people with and without HIV treated with tecovirimat: A systematic review

2026

Mpox poses heightened risks for immunocompromised individuals, particularly people with HIV (PWH), yet evidence on clinical outcomes and antiviral treatment remains limited. We conducted a systematic review in accordance with...

Assessment of knowledge and use of HIV primary and secondary prevention strategies in Portugal: A scoping review

2026

BACKGROUND: Portugal has been committed to achieve UNAIDS target goals by the end of 2030 by improving accessibility of prevention programs to the general population and key populations. However, Portugal...

Integrated service delivery models for triple elimination of mother to child transmission of human immunodeficiency virus, syphilis, and hepatitis B virus: A global systematic review and meta-analysis

2026

BACKGROUND AND OBJECTIVES: Despite global commitment to the World Health Organization triple elimination initiative, evidence on integrated antenatal service delivery models that simultaneously address human immunodeficiency virus (HIV), syphilis, and...

Implementation of therapeutic adherence in adult patients diagnosed with the human immunodeficiency virus: A systematic review

2026

OBJECTIVES: To systematically map and summarize the available knowledge on interventions that promote medication adherence among adult HIV patients and to describe the current state of the art regarding the...

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