SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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SARS-CoV-2 infection in adults and HIV: An update

2022

Aim COVID-19 pandemic caused by SARS-CoV-2 is spreading throughout the world affecting both healthy individuals and people with underlying immune-deficiencies. People living with human immunodeficiency virus (HIV) consist a group...

Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: A network meta-analysis

2022

Background: Global antiretroviral therapy has entered a new era. Integrase strand transfer inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) treatment. Because INSTI has high antiviral efficacy,...

A systematic review of HIV screening programs conducted in pediatric emergency departments in the United States

2022

BACKGROUND: We conducted a systematic review of studies published in peer-reviewed journals on HIV screening programs conducted in pediatric emergency departments (PEDs) in the United States (US) with the objective...

HIV prevention research with U.S. military service members: A systematic review

2022

Introduction: With the goal of maintaining mission readiness, the U.S. Department of Defense monitors a variety of health behaviors among its active duty military service members, including sexual health, HIV, and...

Public availability of HIV-1 drug resistance sequence and treatment data: A systematic review

2022

HIV-1 pol sequences from antiretroviral therapy (ART)-naive and ART-experienced people living with HIV-1 are fundamental to understanding the genetic correlates and epidemiology of HIV-1 drug resistance (HIVDR). To assess the public availability...

Association between online health information-seeking and medication adherence: A systematic review and meta-analysis

2022

Background The evidence of the impact of online health information-seeking (OHIS) on health outcomes has been conflicting. OHIS is increasingly recognised as a factor influencing health behaviour but the impact...

Evidence synthesis evaluating body weight gain among people treating HIV with antiretroviral therapy—A systematic literature review and network meta-analysis

2022

Background This systematic review aimed to compare body weight gain associated outcomes over time between dolutegravir (DTG)-based antiretroviral (ART) regimens to other ART regimens, to compare tenofovir alafenamide (TAF)-based regimens,...

Factors associated with catastrophic health expenditure in sub-Saharan Africa: A systematic review

2022

OBJECTIVE: A non-negligible proportion of sub-Saharan African (SSA) households experience catastrophic costs accessing healthcare. This study aimed to systematically review the existing evidence to identify factors associated with catastrophic health...

Suicidality among people living with HIV from 2010 to 2021: A systematic review and a meta-regression

2022

OBJECTIVE: The association between human immunodeficiency virus (HIV)/AIDS and suicidality is not well understood, partly because of variability in results. This meta-analysis aimed to investigate the predictive value of HIV/acquired...

Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy

2022

PURPOSE OF REVIEW: This review summarizes the recent advancements and future directions of digital pill systems (DPS) – which utilize ingestible sensors to directly measure medication ingestion events in real-time...

Impact of the COVID-19 pandemic on HIV healthcare service engagement, treatment adherence, and viral suppression in the United States: A systematic literature review

2022

The COVID-19 pandemic has necessitated adaptations in how healthcare services are rendered. However, it is unclear how these adaptations have impacted HIV healthcare services across the United States. We conducted...

Gender differences in suicidal ideation, suicide attempts, and suicide death among people living with HIV: A systematic review and meta-analysis

2022

Objective: Although excess mortality, especially suicide, is a critical trait in people living with HIV, consensus about gender differences in these areas is lacking. We conducted meta-analyses to examine gender differences...

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