SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Under-nutrition and associated factors among children infected with human immunodeficiency virus in sub-Saharan Africa: A systematic review and meta-analysis

2022

Background In the developing world, such as the sub-Saharan African region, HIV/AIDS has worsened the impact of under-nutrition in children. HIV infected children are highly vulnerable to under-nutrition. Therefore, the...

Incidence of impaired kidney function among people with HIV: A systematic review and meta-analysis

2022

Background: In the era of combination antiretroviral therapy (ART), the incidence, manifestations and severity of kidney diseases have dramatically changed in people living with HIV (PLWH). Little is known about the...

Interventions to improve early retention of patients in antiretroviral therapy programmes in sub-Saharan Africa: A systematic review

2022

BACKGROUND: Several interventions to improve long term retention (12 months and above) on treatment have been rigorously evaluated in Sub-Saharan Africa (SSA). However, research on interventions to improve retention of...

Factors associated with viral suppression among cisgender women living with human immunodeficiency virus in the United States: An integrative review

2022

Introduction: Women account for 23% of new human immunodeficiency virus diagnoses in the United States, yet remain understudied. Adherence to antiretroviral therapy and consequent viral suppression are keys to preventing human...

Barriers and facilitators to acceptability of the female condom in low- and middle-income countries: A systematic review

2022

BACKGROUND: Sexually transmitted infections, including HIV, remain a significant public health challenge for low- and middle-income countries, and about 111 million unintended pregnancies occur in these countries annually. The female...

A review of sexual transmitted infection rates among sexually assaulted patients that present for care

2022

BACKGROUND: Patients who experience sexual assault are at risk of adverse health outcomes including sexually transmitted infections (STI) and often present to various healthcare centers for post-assault care. Unfortunately, there...

The effect of perinatal HIV and antiretroviral therapy on vascular structure and function in young people: A systematic review and meta-analysis

2022

Background and aims Perinatal HIV infection (PHIV) and prolonged use of antiretroviral therapy (ART) may increase the likelihood of developing subclinical vascular dysfunction at an early age. We conducted a...

Do couple-based interventions show larger effects in promoting HIV preventive behaviors than individualized interventions in couples? A systematic review and meta-analysis of 11 randomized controlled trials

2022

This systematic review and meta-analysis aims to compare the effects of couple-based prevention interventions against individual-level interventions on HIV prevention in randomized controlled trials (RCTs), identify potential moderators, and assess...

Oral health status of children and adolescents living with HIV undergoing antiretroviral therapy: A systematic review and meta-analysis

2022

Antiretroviral therapy (ART) increases the survival of HIV-infected children, but might also bring in oral health-related side effects and increase their risks of oral diseases. The review compared the oral...

Men who have sex with men is the high-risk drug resistance population: A meta-analysis of HIV-1 drug resistance profiles and trends in China

2022

WHAT IS KNOWN AND OBJECTIVE: Except for the transmitted drug resistance (TDR)’s standard sampling and monitoring protocol, China’s HIV-1 pretreatment drug resistance (PDR) and acquired drug resistance (ADR) results vary...

Health-related needs reported by adolescents living with HIV and receiving antiretroviral therapy in sub-Saharan Africa: A systematic literature review

2022

INTRODUCTION: Adolescents living with HIV (ALHIV) on antiretroviral therapy (ART) have specific health needs that can be challenging to deliver. Sub-Saharan Africa (SSA) is home to 84% of the global...

Leveraging resilience-supportive strategies to enhance protective factors in young sexual minority men: A scoping review of HIV behavioral interventions implemented in high-income countries

2022

Behavioral HIV interventions focused on strengthening young sexual minority men’s (SMM) internal (assets) and external (resources) protective factors are promising, yet their evaluation as resilience-supportive strategies to minimize or negate...

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