SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Public health implications of adapting HIV pre-exposure prophylaxis programs for virtual service delivery in the context of the COVID-19 pandemic: A systematic review

2022

BACKGROUND: The novel coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) threatens to disrupt global progress towards HIV epidemic control. Opportunities exist to leverage ongoing...

Systematic review: Development of a person-centered care framework within the context of HIV treatment settings in sub-Saharan Africa

2022

OBJECTIVES: Person-centred care (PCC) meets the needs of individuals by increasing convenience, providing supportive and culturally appropriate services to diverse populations, and engaging families, communities, and stakeholders in planning and...

Prevalence and determinants of suicidal ideation and suicide attempt in people with human immunodeficiency virus in Africa: A systematic review

2022

BACKGROUND: People with human immunodeficiency virus (HIV) are at higher risk of suicidal ideation and suicide attempts. We reviewed the literature for the prevalence and determinants of suicidal ideation and...

A systematic review of risk factors and consequences of nyaope usage: The illicit street drug containing HIV antiretrovirals

2022

South Africa currently has the highest number of cases of HIV in the world. HIV antiretrovirals (ARVs) are publicly available across the country to address this crisis. However, a consequence...

Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: A systematic review and meta-analysis

2022

Background: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines...

Barriers to accessing pre-exposure prophylaxis among women experiencing intimate partner violence in the United States: A systematic literature review

2022

Women experiencing intimate partner violence (IPV) are at increased risk of human immunodeficiency virus (HIV) infection but have limited uptake of pre-exposure prophylaxis (PrEP). We systematically reviewed the existing evidence...

HIV infection does not affect the risk of death of COVID-19 patients: A systematic review and meta-analysis of epidemiological studies

2022

Background: Even during the current Coronavirus Disease 2019 (COVID-19) pandemic, the infection with the Human Immunodeficiency Virus (HIV) continues to pose a major threat, worldwide. In fact, the World Health Organization...

Cost-effective strategies of testing for HIV and sexually transmitted infections (STIs)

2022

Rates of chlamydia, gonorrhea, and infectious syphilis have risen in Canada from 2015 to 2019. An observed decrease in HIV cases has been detected recently, however a reduction in testing...

Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review

2022

Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...

The ‘4th 90’ target as a strategy to improve health-related quality of life of people living with HIV in sub-Saharan Africa

2022

OBJECTIVES: Next to monitoring the clinical health of people living with HIV through the triple 90 targets, a 4th 90 target was proposed in 2016 to improve HIV health-related quality...

Loco-regional treatments for hepatocellular carcinoma in people living with HIV

2022

Hepatocellular carcinoma (HCC) accounts for approximately 75–90% of primary liver cancers and is the sixth most common cancer and the third leading cause of cancer-related deaths worldwide. In the HIV-positive...

Risk of vertical transmission of chronic viral infections after invasive prenatal procedures

2022

OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...

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