SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Safety, tolerability, and metabolic effects of long-acting cabotegravir and rilpivirine in HIV care: A comprehensive review

2025

The use of long-acting cabotegravir and rilpivirine (LA CAB/RPV) is a novel approach to manage human immunodeficiency virus (HIV). This injectable regimen offers benefits such as an improved quality of...

FujiLAM assays for tuberculosis detection in people with HIV: A systematic review and meta-analysis

2025

Background There is a global need for a rapid, accurate, and non-sputum point-of-care (PoC) assay for tuberculosis (TB), especially for people with HIV (PLHIV). The Fujifilm SILVAMP TB LAM (FujiLAM),...

Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review

2025

Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...

Systematic review on the compliance of WHO guidelines in the management of patients with advanced HIV disease in Africa: The case of cryptococcal antigen screening

2025

BACKGROUND: The World Health Organization (WHO) recommended cryptococcal antigen (CrAg) screening for people presenting with advanced HIV disease (AHD) and for those with positive CrAg without evidence of meningitis to...

Thyroid disorders in patients with human immunodeficiency virus infection: A meta-analysis

2025

Background Thyroid disorders have significant clinical sequelae, including impaired growth in children, metabolic abnormalities, and impaired cognitive function. However, available studies on burden of thyroid diseases in people with human...

Risk factors associated with human Mpox infection: A systematic review and meta-analysis

2025

BACKGROUND: Mpox emerged as a significant global public health concern during the 2022-2023 outbreak, impacting populations in both endemic and non-endemic countries. This study reviews and synthesises evidence on the...

Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023

2025

Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...

Interventions and strategies to increase cervical cancer screening, treatment, and retention in care among persons with HIV in low- and middle-income countries: A systematic review

2025

Cervical cancer (CC) and HIV pose two major public health challenges, with low and middle-income countries (LMICs) exhibiting the highest disease burden and mortality rate for both HIV and CC-related...

Gender-based violence syndemics in global health: A systematic review

2025

Global guidance indicates that protections for gender and equity issues, such as gender-based violence (GBV), should be mainstreamed across sectors. One novel strategy that can be leveraged to illustrate the...

Depression and associated factors among human immunodeficiency virus-positive pregnant women in sub-Saharan Africa: Systematic review and meta-analysis

2025

BACKGROUND: Despite its severe impact on both maternal and fetal health, antenatal depression has not received as much attention in the healthcare community as postnatal depression. Comprehensive evidence is very...

Are Candida albicans isolates from people living with HIV more resistant to antifungals? A systematic review and meta-analysis

2025

People living with HIV (PLHIV) often require antifungal medications for the treatment or prevention of infections, which may contribute to the emergence of resistant Candida albicans strains. This systematic review...

Late diagnosis of human immunodeficiency virus (HIV) and its associated factors in Asian countries: A systematic review

2025

Background: Despite widespread public health interventions and research on Human Immunodeficiency Virus (HIV), late diagnosis and presentation into care constitute serious challenges to effective prevention and control of the disease. Asia,...

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