SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: A systematic review and meta-analysis

2022

Background: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines...

Barriers to accessing pre-exposure prophylaxis among women experiencing intimate partner violence in the United States: A systematic literature review

2022

Women experiencing intimate partner violence (IPV) are at increased risk of human immunodeficiency virus (HIV) infection but have limited uptake of pre-exposure prophylaxis (PrEP). We systematically reviewed the existing evidence...

HIV infection does not affect the risk of death of COVID-19 patients: A systematic review and meta-analysis of epidemiological studies

2022

Background: Even during the current Coronavirus Disease 2019 (COVID-19) pandemic, the infection with the Human Immunodeficiency Virus (HIV) continues to pose a major threat, worldwide. In fact, the World Health Organization...

Cost-effective strategies of testing for HIV and sexually transmitted infections (STIs)

2022

Rates of chlamydia, gonorrhea, and infectious syphilis have risen in Canada from 2015 to 2019. An observed decrease in HIV cases has been detected recently, however a reduction in testing...

Transition interventions for adolescents on antiretroviral therapy on transfer from pediatric to adult healthcare: A systematic review

2022

Globally, adolescents living with HIV (ALHIV) experience poor health outcomes such as low retention in care, ART non-adherence and viral non-suppression. These outcomes coincide with the period during and after...

The ‘4th 90’ target as a strategy to improve health-related quality of life of people living with HIV in sub-Saharan Africa

2022

OBJECTIVES: Next to monitoring the clinical health of people living with HIV through the triple 90 targets, a 4th 90 target was proposed in 2016 to improve HIV health-related quality...

Risk of vertical transmission of chronic viral infections after invasive prenatal procedures

2022

OBJECTIVES: Invasive prenatal procedures including amniocentesis, chorionic villus sampling (CVS) can be prenatally indicated for diagnostic purposes. Chronic viral infections with Human Immunodeficiency Virus (HIV), hepatitis C virus (HCV), hepatitis...

Care of sexual and gender minorities in the emergency department: A scoping review

2022

STUDY OBJECTIVE: This scoping review was conducted to collate and summarize the published research literature addressing sexual and gender minority care in the emergency department (ED). METHODS: Using PRISMA-ScR criteria,...

Traditional Chinese medicine for HIV-associated acute herpes zoster: A systematic review and meta-analysis of randomized trials

2022

Background: Herpes zoster (HZ) is a common infection in individuals with acquired immunodeficiency syndrome (AIDS) patients. Traditional Chinese medicine (TCM) has been used widely in clinical practice for HZ, which remains...

HIV serostatus disclosure and its predictors among children living with HIV in Ethiopia: A systematic review and meta-analysis

2022

Background HIV disclosure among children refers to when the caregiver is having disclosed to the child that he or she has HIV specifically. Disclosure significantly improved adherence to treatment and...

Meta-synthesis and science mapping analysis of HIV/HPV co-infection: A global perspective with emphasis on Africa

2022

BACKGROUND: Viral infections are emerging with diverse clinical relevance both in endemic environments and non-endemic regions of the world. Some of the viruses cause co-infections that are of public health...

Best practices to increase the uptake of HIV and HCV testing among people who use drugs

2022

Interventions that provide HIV and/or HCV testing have been offered in a variety of settings. These include community settings such as outpatient drug treatment clinics, mobile clinics, harm reduction services...

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