SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Identifying access barriers to PrEP among cisgender Black/African American women in the United States: A systematic review of the literature

2025

BACKGROUND/OBJECTIVES: Cisgender Black women in the U.S. face disproportionately high HIV rates due to systemic inequities rooted in institutional racism, not individual behaviors. These disparities are particularly severe in the...

Voluntary HIV testing and counselling initiatives in occupational settings: A scoping review

2025

Voluntary HIV testing and counselling (VCT) in the workplace could reach population groups who may be at risk for HIV but may not readily seek out testing from other services....

Concomitant virus infection increases mortality and worsens outcome of acute pancreatitis: A systematic review and meta-analysis

2025

BACKGROUND: Acute pancreatitis (AP) is a major health threat, with a high mortality rate in severe forms. Though alcohol and bile-induced factors are the most common causes, increasing evidence suggests...

Economic evaluations of sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs): A systematic review

2025

BACKGROUND: Sexual and reproductive health (SRH) programmes and services aim to prevent complications of pregnancy and childbirth, unintended pregnancies, unsafe abortions, complications caused by sexually transmitted infections, including HIV, sexual...

Insights into gastrointestinal manifestation of human immunodeficiency virus: A narrative review

2025

Human immunodeficiency virus (HIV) modifies CD4-positive cells, resulting in immunodeficiency and a wide range of gastrointestinal (GI) manifestations. The burden of HIV-related GI illnesses has significantly evolved with the widespread...

Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis

2025

BACKGROUND: Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented. METHODS: We systematically searched six electronic databases, three preprint...

The association between disclosure and antiretroviral therapy among adults living with HIV in China: A systematic review and meta-analysis

2025

BACKGROUND: Antiretroviral therapy (ART) and ART adherence are crucial for preventing HIV transmission and prolonging the lifespan of people living with HIV (PLWH). Serostatus disclosure is a significant factor influencing...

Association between baseline HIV-1 DNA levels and clinical outcomes in people living with HIV: A meta-analysis of cohort studies

2025

To assess the prognostic value of baseline HIV-1 DNA levels, a meta-analysis was conducted according to the PROSPERO protocol (CRD42024619050) based on data from studies published until March 4, 2025....

Determination of depression prevalence in pregnant women living with HIV aged 18 years and older: A meta-analysis study

2025

BACKGROUND: Pregnant women living with HIV are known to be at higher risk of depression than pregnant women without HIV. Accompanied by a systematic literature review, the aim of this...

Global prevalence of advanced HIV disease in healthcare settings: A rapid review

2025

Introduction Recent studies have indicated a high enduring burden of advanced HIV disease, but estimates across regions and settings are lacking. The aim of this study was to estimate the...

The burden of HPV infections and HPV-related diseases among people with HIV: A systematic literature review

2025

Human papillomavirus (HPV) is associated with a significant global burden of precancerous lesions and cancer. People with HIV (PWH) are at higher risk of HPV infection and HPV‐related diseases. This...

Adherence definitions, measurement modalities, and psychometric properties in HIV, diabetes, and nutritional supplementation studies: A scoping review

2025

Measuring adherence has been a priority for researchers to help inform effective care for patients regularly consuming medications for chronic conditions. As a widely accepted “gold standard” adherence measure or...

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