SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Experiences and perceptions on antiretroviral therapy adherence and non-adherence: A scoping review of young people living with HIV in sub-Saharan Africa

2025

BACKGROUND: Young people in sub-Saharan Africa (SSA) shoulder a disproportionate burden of global HIV. We conducted a scoping review to map the research on the experiences and perceptions of young...

Intimate partner violence among women living with HIV in East Africa: A systematic review and meta-analysis

2025

Background Intimate partner violence (IPV) is a widespread yet often unrecognized problem that affects millions of women worldwide. It is prevalent among marginalized individuals, such as women living with HIV....

Free antiretrovirals as a key tool against the HIV pandemic: A systematic review

2025

BACKGROUND/OBJECTIVES: Access to antiretroviral (ARV) drugs remains a critical challenge in achieving the WHO/UNAIDS 95-95-95 targets, with medication costs representing a substantial barrier. This systematic review evaluates the effect of...

Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review

2025

Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...

Network meta-analytical investigations of the performance of HIV combination prevention strategies for Indigenous populations

2025

BACKGROUND: Indigenous populations worldwide face a disproportionate burden of HIV due to structural inequities, cultural marginalization, and limited access to health services. Despite growing recognition of the need for culturally...

The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis

2025

The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...

Approaches used to monitor the effectiveness of community-led monitoring programmes: A scoping review to inform HIV programmes

2025

INTRODUCTION: Community-led monitoring (CLM) for HIV is a technique implemented by local community-led organizations and groups that systematically gather data about HIV services to advocate for improvement. This review was...

Unveiling the underestimated prevalence of HIV, HBV and TB triple infection in Asia, South America, and Africa: A systematic review and meta-analysis

2025

BACKGROUND: Human immunodeficiency virus (HIV) is a genus of retroviruses that targets immune cells and may eventually cause immune-deficiency illness. Triple infection of HIV/hepatitis B virus (HBV) /tuberculosis (TB) leads...

Community-based interventions against HIV-related stigma: A systematic review of evidence in Sub-Saharan Africa

2025

Background: HIV-related stigma remains a key barrier to the attainment of the UNAIDS global goal of ending AIDS by 2030. Due to the social and contextual nature of HIV-related stigma, community-based...

mRNA vaccines against HIV: Hopes and challenges

2025

BACKGROUND: Since the introduction of the first licensed mRNA-based vaccines against COVID-19, there has been significant interest in leveraging this technology for other vaccines. An unprecedented surge of mRNA vaccines...

Measurement and evaluation of community engagement in complex, chronic medical conditions: HIV and obesity as exemplar conditions

2025

Objective To systematically review, describe, and compare quantitative measures of community engagement in obesity and HIV prevention research. Materials & Methods A systematic review adhering to PRISMA and PROSPERO guidelines...

Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV—A review

2025

Introduction HIV-1 remains a major global health challenge, impacting approximately 39 million people worldwide. Although antiretroviral therapy has substantially reduced HIV incidence and enhanced the quality of life for those living...

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