SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Unveiling the underestimated prevalence of HIV, HBV and TB triple infection in Asia, South America, and Africa: A systematic review and meta-analysis

2025

BACKGROUND: Human immunodeficiency virus (HIV) is a genus of retroviruses that targets immune cells and may eventually cause immune-deficiency illness. Triple infection of HIV/hepatitis B virus (HBV) /tuberculosis (TB) leads...

A global review of national guidelines of post-exposure prophylaxis for the prevention of HIV

2025

INTRODUCTION: The World Health Organization (WHO) recommends the use of antiretroviral drugs as post-exposure prophylaxis (PEP) for preventing HIV acquisition for occupational and non-occupational exposures. To inform the development of...

A scoping review of factors that affect unmet dental service needs among people living with HIV/AIDS

2025

BACKGROUND: There was an inequality in utilizing oral and dental healthcare utilization. Although people living with HIV need more oral and dental services they receive less and they have many...

Impact of HIV infection on hepatocellular carcinoma: A long-term prognostic analysis

2025

Purpose: This study aims to explore the influence of human immunodeficiency virus (HIV) infection on the prognosis of patients with hepatocellular carcinoma (HCC). Methods: According to the search strategy, we...

Self-reported sleep disturbances among people living with HIV in China: A systematic review and meta-analysis

2025

Objective: People living with HIV (PLWH) commonly face a range of health issues, among which sleep disturbances are common and are related to adverse health outcomes. This review aims to assess...

Experiences and perceptions on antiretroviral therapy adherence and non-adherence: A scoping review of young people living with HIV in sub-Saharan Africa

2025

BACKGROUND: Young people in sub-Saharan Africa (SSA) shoulder a disproportionate burden of global HIV. We conducted a scoping review to map the research on the experiences and perceptions of young...

Intimate partner violence among women living with HIV in East Africa: A systematic review and meta-analysis

2025

Background Intimate partner violence (IPV) is a widespread yet often unrecognized problem that affects millions of women worldwide. It is prevalent among marginalized individuals, such as women living with HIV....

Free antiretrovirals as a key tool against the HIV pandemic: A systematic review

2025

BACKGROUND/OBJECTIVES: Access to antiretroviral (ARV) drugs remains a critical challenge in achieving the WHO/UNAIDS 95-95-95 targets, with medication costs representing a substantial barrier. This systematic review evaluates the effect of...

Use of self-test to increase HIV testing among men who have sex with men and transgender women—Overview of systematic reviews

2025

ABSTRACT Human Immunodeficiency Virus (HIV) infection is stigmatizing, especially for key populations, who are disproportionately affected by Sexually Transmitted Infections (STIs). The stigma and discrimination suffered by these groups are...

Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis

2025

Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...

Lenacapavir: A twice-yearly injectable for HIV preexposure prophylaxis

2025

OBJECTIVE: To review the efficacy and safety of lenacapavir for the prevention of HIV-1 infection. DATA SOURCES: Clinical trials and review articles were obtained through August 2025 using search terms...

Deep sequencing reveals underestimated burden of integrase inhibitor resistance mutations in people living with HIV: A global individual patient data meta-analysis

2025

Integrase strand transfer inhibitors (INSTIs) have emerged as cornerstone agents in global antiretroviral therapy, though growing drug resistance presents clinical challenges. Conventional Sanger sequencing may underestimate the burden of low-frequency...

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