SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-Infected adults: A systematic review and meta-analysis

2020

Background: The HIV associated mortality is decreasing in most countries due to the widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder (HAND) remains a problematic issue that lowers the...

Technology-Based Interventions to Increase Point-of-Care HIV Testing and Linkage to Care Among Youth in the US: A Systematic Review

2020

HIV testing rates remain low among youth ages 13-24 in the US, with only 55% of HIV-positive youth aware of their serostatus. We conducted a systematic review to assess the...

Global Research on Quality of Life of Patients with HIV/AIDS: Is It Socio-Culturally Addressed? (GAP(RESEARCH))

2020

Quality of life (QOL) has been considered as an important outcome indicator in holistic care for HIV-infected people, especially as HIV/AIDS transforms from a fatal illness to a chronic condition....

A review of potential microbiome-gut-brain axis mediated neurocognitive conditions in persons living with HIV

2020

The microbiome-gut-brain axis, or the various interactions between the gut microbiome and the brain, has been of recent interest in the context of precision medicine research for a variety of...

Magnitude of Cryptococcosis among HIV patients in sub-Saharan Africa countries: A systematic review and meta-analysis

2020

BACKGROUND: Cryptococcus is encapsulated opportunistic yeast that causes life threatening meningoencephalitis of patients with human immunodeficiency virus (HIV). The magnitude of Cryptococcosis among HIV patients varies from 1–10% in Western...

Changes in smoking patterns after HIV diagnosis or antiretroviral treatment initiation: A global systematic review and meta-analysis

2020

Abstract Background Tobacco consumption is more life-threatening in people living with human immunodeficiency virus (HIV) than within the general population; therefore, people living with HIV (PLWH) should be highly motivated...

Neuropathy complication of antiretroviral therapy in HIV/AIDS patients

2020

OBJECTIVES: Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects 40% of HIV-infected individuals treated with antiretroviral therapy (ART). The most salient symptom of the neuropathy is pain, which frequently is...

Efficacy of HIV interventions in African fishing communities: A systematic review and qualitative synthesis

2020

OBJECTIVES: This systematic review aims to qualitatively synthesise existing evidence on the efficacy of HIV interventions in African fishing communities. METHODS: Five databases (NCBI PubMed, EMBASE, Web of Science Core...

Diagnostic accuracy of serum (1,3)-beta-D-glucan for Pneumocystis jirovecii pneumonia: A systematic review and meta-analysis

2020

Serum 1,3-β-d-glucan (BG) assay may be helpful as a marker for the diagnosis of Pneumocystis jiroveci pneumonia (PJP) and invasive fungal infection (IFI). We conducted a systematic review to assess the diagnostic...

Injecting risk behaviours amongst people who inject drugs: A global multi-stage systematic review and meta-analysis

2020

BACKGROUND: Injecting risk behaviour, such as receptive sharing of injecting equipment and/or re-using one’s equipment, is associated with bloodborne virus transmission and infections in people who inject drugs (PWID). We...

Attributes of HIV infection over decades (1982–2018): A systematic review and meta-analysis

2020

Understanding the risk factors for HIV infection is the foundation of successful preventive strategies, which must bundle sociocultural, behavioural and biomedical interventions to halt disease transmission. We aimed in this...

Prevalence estimates of human immunodeficiency virus (HIV) infection among visceral leishmaniasis infected people in Northwest Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: In Ethiopia, by the end of 2018, an estimated 690,000 people are infected with HIV and the annual cases of Visceral Leishmaniasis (VL) is estimated to be between 4000...

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