SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Cancer in older adults living with HIV

2026

Key take-home messages Evidence shows that cancer risk among older people living with HIV is increased for some cancers (e.g., anal, lung, liver). Earlier initiation of antiretroviral therapy (ART) following...

Geospatial Approaches to HIV Care: a Scoping Review of Asset Mapping

2026

PURPOSE OF REVIEW: Asset mapping aims to engage members of a community to explore and map assets that are solutions to social issues such as homelessness or access to health...

Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials

2026

BACKGROUND: HIV-associated lipodystrophy leads to visceral fat accumulation, metabolic complications, body image concerns, medication non-adherence, and increased cardiovascular risks. We thought to assess the effects of Tesamorelin, a synthetic growth...

Models of primary health care for people living with HIV

2026

Key take-home messages

Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis

2026

BACKGROUND: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). METHODS: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in...

HIV testing during systematic screening for tuberculosis among household contacts in high-tuberculosis burden settings: A systematic review and meta-analysis

2026

BACKGROUND: Tuberculosis household contacts are at elevated risk of HIV, and systematic screening for tuberculosis is an opportunity for people to know their status. We aimed to assess the coverage...

Preferences for long-acting antiretroviral therapy among people with HIV: A systematic review of discrete choice experiments

2026

BACKGROUND: Long-acting antiretroviral therapy (LA-ART) is emerging as a promising strategy to enhance treatment satisfaction and improve the quality of life for people living with HIV (PLWH). A comprehensive understanding...

Racism, homophobia, and the sexual health of young Black men who have sex with men in the United States: A systematic review

2025

Black gay, bisexual, and other men who have sex with men (BMSM) experience the highest rates of HIV acquisition annually out of any population in the United States, and young...

Risk factors associated with human Mpox infection: A systematic review and meta-analysis

2025

BACKGROUND: Mpox emerged as a significant global public health concern during the 2022-2023 outbreak, impacting populations in both endemic and non-endemic countries. This study reviews and synthesises evidence on the...

Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: Evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023

2025

Background: Virological failure (VF) significantly threatens the efficacy of antiretroviral therapy (ART) programs in East Africa. This systematic review and meta-analysis assess the prevalence and predictors of VF among individuals living...

Interventions and strategies to increase cervical cancer screening, treatment, and retention in care among persons with HIV in low- and middle-income countries: A systematic review

2025

Cervical cancer (CC) and HIV pose two major public health challenges, with low and middle-income countries (LMICs) exhibiting the highest disease burden and mortality rate for both HIV and CC-related...

Gender-based violence syndemics in global health: A systematic review

2025

Global guidance indicates that protections for gender and equity issues, such as gender-based violence (GBV), should be mainstreamed across sectors. One novel strategy that can be leveraged to illustrate the...

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