SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Interest in and preference for long-acting injectable pre-exposure prophylaxis among men who have sex with men, trans* individuals, and cisgender heterosexual women: A global systematic review and meta-analysis

2025

BACKGROUND: Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) offers potentials for expanding PrEP coverage and improving public health outcomes. This study synthesizes evidence on the prevalence and determinants of interest in and...

Integration models for delivering COVID-19 vaccines through HIV services in low-and middle-income countries: A scoping review

2025

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) remains a major global public health issue. People living with HIV (PLHIV) are among the vulnerable groups facing a higher risk of severe outcomes....

Food consumption and cardiovascular risk in children and adolescents living with HIV: A systematic review

2025

The aim of this systematic review was to summarize the dietary intake of children and adolescents living with HIV and its association with cardiovascular risk factors. PubMed/MEDLINE, Scopus, Web of...

HIV risk score and prediction model in the United States: A scoping review

2025

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

Worldwide epidemiology of Cyclospora cayetanensis in HIV/AIDS patients: A systematic review and meta-analysis

2025

BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...

Drug-drug interactions in transgender patients receiving antiretroviral and hormonal therapy: A systematic review of clinical studies and reports

2025

Transgender individuals, whose gender identity differs from their assigned sex at birth, often undergo pharmacotherapy, including hormone therapy (HT), as part of their gender-affirming care. This pharmacotherapy, particularly when combined...

Pre-exposure prophylaxis uptake among Black/African American men who have sex with other men in Midwestern, United States: A systematic review

2025

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

HIV, hepatitis, and syphilis self-testing among adolescents and young adults: A systematic review and meta-analysis

2025

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

Effect of human immunodeficiency virus self-testing (HIVST) on HIV and STI testing uptake among men who have sex with men (MSM): A systematic review and meta-analysis of randomized controlled trials

2025

Objectives: The objective of this review was to assess the effectiveness of HIVST in terms of increasing HIV testing, early detection of HIV, and sexually transmitted infections among MSM via...

Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review

2025

Background Identification and stratification of risk factors for stroke among individuals living with HIV (PLWH) will facilitate primary prevention and prognostication, as well as strategies aimed at optimizing neurorehabilitation. This...

HIV status and the risk of typhoid fever and iNTS: A systematic review and meta-analysis

2025

OBJECTIVES: The WHO recommends prioritising people living with HIV (PLHIV) for typhoid vaccination, but evidence for increased typhoid fever risk is inconsistent. We aimed to evaluate whether HIV infection alters...

Prevalence of low-level viremia and related influencing factors among people living with HIV in China: A systematic review and meta-analysis

2025

Introduction The promotion and application of ART have significantly reduced the mortality rate of AIDS patients in China, but the problem of LLV that follows cannot be ignored. LLV is...

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