SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Altruism: Scoping review of the literature and future directions for HIV cure-related research

2020

INTRODUCTION: The question of what motivates people to participate in research is particularly salient in the HIV field. While participation in HIV research was driven by survival in the 1980’s...

Recruitment of US adolescents and young adults (AYA) into human immunodeficiency virus (HIV)-related behavioral research studies: A scoping review

2020

PURPOSE OF REVIEW: The objective of this scoping review was to examine the range of published evidence on recruitment approaches and outcomes of US adolescents and young adults (AYA) ages...

Clinical and public health implications of HIV-genetic diversity and drug resistance mutations in Angola: A systematic review

2020

HIV-1 genetic diversity and drug resistance mutations (DRMs) remain a public health concern mainly in low- and middle-income countries. In this review, we estimated the HIV-1 molecular evolution over the...

Course of disease and clinical outcome of infective endocarditis in HIV-infected individuals: A systematic review and meta-analysis

2020

Infective endocarditis (IE) causes substantial morbidity and mortality if untreated. The clinical course of IE might be different in HIV-positive patients as a result of immune dysfunction. This systematic review...

HIV patients retention and attrition in care and their determinants in Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: There is paucity of evidence on the magnitude of HIV patients’ retention and attrition in Ethiopia. Hence, the aim of this study was to determine the pooled magnitude of...

Cervical cancer screening uptake and associated factors among HIV-positive women in Ethiopia: A systematic review and meta-analysis

2020

Background Cervical cancer is the leading cause of cancer deaths among women in developing countries. Since cervical cancer is a preventable disease, screening is an important control and prevention strategy,...

The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI): A systematic review of observational epidemiological studies

2020

BACKGROUND: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure independently and...

Interventions to reduce social isolation and loneliness among men who have sex with men

2020

Key take-home messages Social isolation and loneliness are significantly associated with all-cause mortality in the general population. A recent study among gay and bisexual men who have sex with men...

Factors associated with HIV testing among people who inject drugs: A meta-analysis

2020

HIV testing is the first step to early identification, treatment and management of HIV infection among people involved in high-risk behaviors specifically drug injection. Achieving declines in morbidity and mortality...

The recovery rate from severe acute malnutrition among under-five years of children remains low in sub-Saharan Africa. A systematic review and meta-analysis of observational studies

2020

BACKGROUND: Globally, Severe Acute Malnutrition (SAM) has been reduced by only 11% over the past 20 years and continues to be a significant cause of morbidity and mortality. So far,...

Paradoxes in the phenotype, frequency and roles of myeloid-derived suppressor cells during HIV infection

2020

Myeloid-derived suppressor cells (MDSCs) are heterogeneous groups of pathologically activated myeloid cells with potent immunosuppressive function. Due to their role in negatively regulating the immune system, MDSCs have been strongly...

Intestinal parasitic infections and associated factors among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

2020

BACKGROUND: Intestinal parasitic infections are major public health problems throughout the world, particularly in people living with HIV/AIDS. People living with HIV/AIDS are vulnerable groups for a variety of diseases,...

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