SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Implementation of Cholesterol-Lowering Therapy to Reduce Cardiovascular Risk in Persons Living with HIV

2020

The widespread availability of highly effective antiretroviral therapies has reduced mortality from opportunistic infections in persons living with HIV (PLHIV), resulting in an increase in atherosclerotic cardiovascular disease (ASCVD) and...

Mental health research in Botswana: a semi-systematic scoping review

2020

Mental and substance use disorders are a leading cause of disability worldwide. Despite this, there is a paucity of mental health research in low- and middle-income countries, especially in sub-Saharan...

What is the most appropriate induction regimen for the treatment of HIV-associated Cryptococcal meningitis when the recommended regimen is not available? Evidence from a network meta-analysis

2020

Aims: Our object was to find the most appropriate, most effective, and most readily available of four induction regimens for HIV-associated cryptococcal meningitis (CM) (Regimen A: 1 week of AmB...

Risk factors associated with seropositivity for Toxoplasma gondii in population-based studies among immunocompromised patients (pregnant women, HIV patients and children) in West African countries, Cameroon and Gabon: A meta-analysis

2020

Toxoplasmosis in immunocompromised individuals can be life threatening. The information needed for proper control and management strategies in endemic West African countries is lacking, hence a systematic review and meta-analysis...

Coronavirus disease 2019 (COVID-19) outcomes in HIV/AIDS patients: A systematic review

2020

OBJECTIVES: The aim of the study was to systematically review current studies reporting on clinical outcomes in people living with HIV (PLHIV) infected with severe acute respiratory syndrome coronavirus 2...

Mortality among people With opioid use disorder: A systematic review and meta-analysis

2020

BACKGROUND AND AIMS: Opioids are among the most commonly used class of illicit drugs. We aimed to produce pooled estimates of mortality risks among people with opioid use disorder (OUD),...

Mobile health promotion of human immunodeficiency virus self-testing in the United States

2020

Background: Human immunodeficiency virus (HIV) self-testing could overcome barriers associated with traditional HIV testing and increase people’s awareness of their serostatus. Mobile health, which utilizes mobile wireless technology, could alleviate...

The risk of HIV among women after acquiring a sexually transmitted infection (STI) and considerations for their use of PrEP

2020

Key take-home messages A recent study in the U.S. found that most women who were diagnosed with HIV did not have a reported STI in the past. Another U.S. study...

Adolescent participation in HIV research: Consortium experience in low and middle-income countries and scoping review

2020

Adolescents in low and middle-income countries (LMICs) have a high prevalence of HIV, therefore, it is important that they are included in HIV research. However, ethical challenges regarding consent can...

HIV, vascular risk factors, and cognition in the combination antiretroviral therapy era: A systematic review and meta-analysis

2020

OBJECTIVES: Mounting evidence indicates that vascular risk factors (VRFs) are elevated in HIV and play a significant role in the development and persistence of HIV-associated neurocognitive disorder. Given the increased...

Are patient outcomes improved by models of professionally-led community HIV management which aim to be person-centred? A systematic review of the evidence

2020

UNAIDS advocates person-centred care (PCC) for people living with HIV/AIDS (PLWHA) to improve outcomes and wellbeing. We appraised the evidence of person-centred models of community HIV care delivered or led...

Global prevalence and burden of HIV-associated neurocognitive disorder: A meta-analysis

2020

OBJECTIVES: We aimed to characterise the prevalence and burden of HAND and assess associated factors in the global population with HIV. METHODS: We searched PubMed and Embase for cross-sectional or...

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