SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

Background Vaccine acceptance among People Living with HIV (PLWH) is crucial for managing and mitigating the spread of infectious diseases, including Mpox. This systematic review and meta-analysis assess the rate...

Retention and adherence to daily oral pre-exposure prophylaxis (PrEP) are critical for effective HIV prevention; however, YMSM exhibit lower rates of both compared to other populations. This is important because...

OBJECTIVE: This study evaluates the efficacy, safety, and cost-effectiveness of INSTI-based antiretroviral regimens compared to the national standard first-line treatment EFV/3TC/TDF for HIV/AIDS in China. The aim is to guide...

Background: The use of antiretroviral therapy (ART) has improved the lives of people living with HIV (PLWH). However, its use is associated with secondary complications, notably hepatotoxicity. This systematic review and...

BACKGROUND: The long-acting injectable regimen of cabotegravir plus rilpivirine (CAB/RPV) emerged as an alternative to oral standard-of-care integrase strand transfer inhibitor (INSTI)-based regimens for individuals with adherence challenges or preference...

BACKGROUND: Human immunodeficiency virus (HIV) persists as a formidable and far – reaching threat without a cure. T cells are crucial for antiviral immunity and pathology in HIV patients, with...

Neuroimaging studies have identified brain structural and functional alterations in HIV-infected patients; however, the results are inconsistent. This study aimed to characterize the effects of HIV infection on regional gray...

Loss to follow-up (LTFU) among people living with HIV (PLHIV) is a concerning reality in various healthcare services and can occur at any stage of HIV care. LTFU can lead...

People with human immunodeficiency virus (PWH) face increased health risks beyond those directly linked to HIV infection, including reduced cardiorespiratory fitness (CRF), cardiovascular disease, and accelerated aging. Physical exercise, particularly...

Introduction Viral load suppression is essential for reducing human immunodeficiency virus (HIV) related morbidity and mortality. To eliminate the HIV epidemic and enhance adherence to antiretroviral therapy (ART) globally, the...

The risk of sexual transmission of HIV in serodiscordant couples when the partner living with HIV (PLHIV) uses antiretroviral therapy (ART) and maintains a suppressed viral load (VL) (< 200...

BACKGROUND: The World Health Organization (WHO) recommends antiretroviral therapy (ART) containing two nucleoside reverse transcriptase inhibitors (NRTIs) as backbone. WHO recommends tenofovir disoproxil fumarate combined with lamivudine or emtricitabine as...