SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Resilience in young people living with HIV in low to middle-income countries: a critical review

2025

HIV continues to be a significant global health issue, with 39 million people living with HIV in 2022, including 1.3 million new infections. Of those, 27% were young people aged...

A global review of national guidelines of post-exposure prophylaxis for the prevention of HIV

2025

INTRODUCTION: The World Health Organization (WHO) recommends the use of antiretroviral drugs as post-exposure prophylaxis (PEP) for preventing HIV acquisition for occupational and non-occupational exposures. To inform the development of...

A review of network models for HIV spread

2025

BACKGROUND: HIV/AIDS has been a global health crisis for over 4 decades. Network models, which simulate human behavior and intervention impacts, have become an essential tool in guiding HIV prevention...

Causes of hospitalisation among people living with HIV worldwide, 2014-23: A systematic review and meta-analysis

2025

Background: Despite improved access to antiretroviral therapy (ART), HIV-related morbidity and mortality remain high. A previous review (2007-14) found that AIDS-related illnesses were the leading causes of hospitalisations. We aimed to...

Preventing unintended pregnancies and HIV through self-care interventions in east and southern Africa: Findings from a structured review

2025

OBJECTIVE: To identify promising interventions targeting young people in East and Southern Africa through self-care practices, with a focus on prevention of unintended pregnancies and HIV and develop four evidence-based...

Technology-based HIV prevention interventions for men who have sex with men: Systematic review and meta-analysis

2025

BACKGROUND: There remain unmet HIV prevention needs in China, particularly among gay, bisexual, and other men who have sex with men. Technology-based interventions are increasingly used in HIV prevention worldwide....

Technology-assisted interventions in the delivery of HIV prevention, care, and treatment services in sub-Saharan Africa: Scoping review

2025

BACKGROUND: Sub-Saharan Africa (SSA) accounts for up to 67% of the global HIV burden yet grapples with health system challenges like distant health facilities, low doctor-to-patient ratio, and poor or...

Prevalence of and risk factors for suicidal ideation among perinatal women with HIV infection: A systematic review, meta-analysis, and meta-regression

2025

Background The prevalence of suicidal ideation (SI) among HIV-positive pregnant women is a complex issue influenced by multiple risk factors. By addressing these risk factors and focusing on vulnerable regions,...

Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of “Universal Test and Treat”: A systematic review and meta-analysis

2025

INTRODUCTION: The “Universal Test and Treat” (UTT) era for antiretroviral therapy (ART) increased HIV service delivery to children and adolescents aged 0-19 with HIV. The goal is to reach ƒ%95%...

User preferences on long-acting pre-exposure prophylaxis for HIV prevention in Eastern and Southern Africa: A scoping review

2025

BACKGROUND: Novel formulations for pre-exposure prophylaxis (PrEP) such as injectables, implants, and intravaginal rings are emerging as long-acting alternatives to daily pills for the prevention of HIV. Eastern and Southern...

Male circumcision and HIV risk compensation among men who have sex with men: A systematic review and meta-analysis

2025

Male circumcision (MC) has been shown to reduce the risk of HIV infection among men who have sex with men (MSM) in a recent randomised controlled trial. A question that...

Effects of massage therapy on anxiety, depression, stress, pain, quality of life, and immune aspects in people living with HIV: A systematic review and meta-analysis

2025

Massage therapy has been explored as a complementary intervention for people living with HIV, with potential effects on emotional, physical, and immune system parameters. This systematic review, conducted following Preferred...

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