SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Measuring mobility in HIV research in sub-Saharan Africa: A scoping review

2025

INTRODUCTION: Mobility-from overnight travel to permanent migration-can reduce service access and increase HIV risk, driving the epidemic in sub-Saharan Africa (SSA). This scoping review described mobility measures used in HIV...

Mental health interventions for young pepole living with HIV/AIDS in sub-Saharan Africa: A systematic review

2025

Introduction: Young people (aged 15-24) living with HIV/AIDS (YPLHIV) in sub-Saharan Africa (SSA) experience higher rates of mental health conditions compared to their uninfected peers. Research and practitioners have expressed...

How do migrants living with HIV adhere to the HIV care process in high-income countries? A systematic review

2025

BACKGROUND: In high-income countries (HICs), migrants living with HIV (MLHIV) are more likely than other HIV subpopulations to encounter problems which hamper their adherence to the care process; these include...

Association between cerebrospinal fluid CXCL10 and neurocognitive disorders in people living with HIV: A meta-analysis

2025

Background C-X-C motif chemokine ligand 10 (CXCL10) is implicated in HIV-associated neuroinflammation, yet its association with HIV-associated neurocognitive disorders (HAND) remains unclear. We conducted a meta-analysis to evaluate cerebrospinal fluid...

Oral pre-exposure prophylaxis retention among men who have sex with men and transgender persons: Systematic review and meta-analysis

2025

Successful implementation of oral pre-exposure prophylaxis (PrEP) requires retention in PrEP care among those with an increased likelihood of HIV. This study aimed to estimate the proportion of retention on...

Multidrug resistance tuberculosis in the context of co-infection in Ethiopia: A systematic review and meta-analysis

2025

The rise of multidrug-resistant tuberculosis (MDR-TB) remains a critical public health challenge, particularly in developing countries like Ethiopia. This systematic review and meta-analysis aimed to estimate the pooled prevalence of...

Loneliness and social isolation in people with HIV

2025

PURPOSE OF REVIEW: Antiretroviral therapy (ART) has significantly extended the life expectancy of people with HIV (PWH). However, as this population ages, they face increased risk of social isolation and...

Barriers to HIV pre-exposure prophylaxis uptake for men who have sex with both men and women: A global scoping review

2025

BackgroundAlthough PrEP is a highly effective HIV prevention method, some groups are underrepresented in PrEP uptake. Much HIV prevention research groups gay, bisexual and other men who have sex with...

Effectiveness of digital health interventions in promoting the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM): A systematic review of randomized controlled trials

2025

PURPOSE OF REVIEW: Digital health interventions have demonstrated great potential to advance HIV prevention and care. However, their effectiveness in improving the pre-exposure prophylaxis (PrEP) care continuum has not yet...

A scoping review on HCV screening strategies: Population to screen and the test types

2025

BACKGROUND: Hepatitis C virus (HCV) is a genetically diverse blood-borne pathogen causing liver inflammation and damage. It is one of the global public health problems responsible for claiming thousands of...

The prevalence of dyslipidemia and its correlation with anti-retroviral therapy among people living with HIV in China: A systematic review and meta-analysis

2025

Background Dyslipidemia, a risk factor of cardiovascular diseases, was a long-term adverse event of anti-retroviral drugs. Efavirenz (EFV) and lopinavir/ritonavir (LPV/r) were recommended and the widely used antiretroviral drugs while...

Transition From adolescent to adult care for young people living with HIV: A systematic review of needs, barriers, and interventions

2025

Young people living with HIV (YPLHIV) aged 15-24 years represent over 25% of new HIV infections globally. They face significant challenges in transitioning from pediatric to adult care. Despite guidelines...

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