SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review of infodemiology studies using artificial intelligence: Social media posts on HIV preexposure prophylaxis

2025

OBJECTIVES: To explore how artificial intelligence (AI) can enhance infodemiology, which distributes and scans information in the electronic medium, to process social media posts for HIV preexposure prophylaxis (PrEP). DESIGN:...

Safer opioid supply clients’ values and preferences: A systematic review and thematic synthesis of qualitative research

2025

QUESTION: What are the values and preferences of safer opioid supply clients? STUDY SELECTION AND ANALYSIS: We conducted a systematic review of qualitative studies on safer opioid supply client experiences...

Ambivalent experiences of people in treatment for tuberculosis-HIV coinfection: A meta-synthesis of qualitative studies

2025

This study examined the scientific literature, by means of a systematic review with meta-synthesis (PROSPERO No. CRD42023410141), to discover the experiences of people undergoing treatment for tuberculosis-HIV coinfection. Ten databases...

HIV and tuberculosis co-infection in non-European migrants in Europe: A systematic review and meta-analysis

2025

Background Even though HIV-TB co-infection is an emerging public health issue among migrants in European countries, the number of related articles has shown a decreasing trend. Methods To better estimate...

Global and regional molecular epidemiology of HIV-1 among men who have sex with men: A systematic review and meta-analysis

2025

Objectives The diversity of HIV-1 genotypes among Men who have sex with men (MSM) globally has changed considerably. The purpose of this study to assess the global prevalence of HIV-1...

Evaluating the impact of COVID-19 on the HIV care continuum across global income levels: A mixed-methods systematic review

2025

BACKGROUND: The COVID-19 pandemic caused significant disruptions to global healthcare systems, including essential services along the HIV care continuum (HCC). While several studies have examined these impacts in specific countries...

Moxibustion for human immunodeficiency virus and acquired immunodeficiency syndrome and its complications: A systematic review of randomized controlled trials

2025

OBJECTIVE: To comprehensively evaluate randomized controlled trials (RCTs) investigating the effects of moxibustion on people with human immunodeficiency virus (HIV) disease. METHODS: A systematic search was conducted across eight electronic...

Structural and socio-cultural barriers to HIV prevention tools among key populations: A scoping review

2025

INTRODUCTION: Despite decades of HIV prevention efforts, key populations – MSM, transgender people, PWUD, sex workers, and migrants – remain disproportionately affected by HIV. Although prevention tools are widely available,...

Evaluating equity reporting within systematic reviews of pre-exposure prophylaxis (PrEP)

2025

BACKGROUND: Pre-exposure prophylaxis (PrEP) is a medicine that can reduce HIV transmission. Given the disproportionate impact of HIV on minority communities, health equity is an important consideration in PrEP research....

Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis

2025

INTRODUCTION: Chronic kidney disease is a major public health concern among people living with human immunodeficiency virus (PLWHIV) who are taking tenofovir disoproxil fumarate-based regimen. Despite the available evidence showing...

Retention in care after transition to adult care for adolescents and young adults with HIV: A systematic review and meta-analysis

2025

Objective: To evaluate the retention rates of adolescents and young adults (aged 10-25 years) living with HIV during the transition to adult HIV care. Methods: The study involved 15 cohort studies conducted...

Impacts of the COVID-19 pandemic on the HIV care continuum and associated factors in high-income nations: A mixed-methods systematic review

2025

The COVID-19 pandemic has significantly impacted the HIV care continuum (HCC), presenting challenges while also driving positive transformations globally. This study examines the impact of the COVID-19 pandemic on HCC...

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