SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevention of mother-to-child HIV transmission cascade in China: A systematic review and meta-analysis

2016

INTRODUCTION: The Chinese government has invested US$140 million annually on prevention of mother-to-child transmission (PMTCT) of HIV. This study evaluates the programme by examining the improvements in programme coverage HIV...

The effect of alcohol consumption on ART adherence and sexual risk behaviours among men who have sex with men

2016

Key take-home messages Among people living with HIV, alcohol consumption can have an impact on viral load and CD4 counts and affect adherence to antiretroviral regimens. Many studies have found...

The causative agents in infective endocarditis: A systematic review comprising 33,214 cases

2016

Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological...

Effective non-drug interventions for improving outcomes and quality of maternal health care in sub-Saharan Africa: A systematic review

2016

BACKGROUND: Many interventions have been implemented to improve maternal health outcomes in sub-Saharan Africa (SSA). Currently, however, systematic information on the effectiveness of these interventions remains scarce. We conducted a...

Why tell children: A synthesis of the global literature on reasons for disclosing or not disclosing an HIV diagnosis to children 12 and under

2016

While the psychological and health benefits of knowing one’s HIV diagnosis have been documented for adults and adolescents, practice is still in development for younger children. Moderating conditions for whether...

Participation of African Americans in e-Health and m-Health Studies: A Systematic Review

2016

BACKGROUND: African Americans (AA) experience high levels of health disparities for several diseases, yet remain underrepresented in clinical trials and other types of research. The high ownership of smartphones among...

HIV-1 and the Mycobacterium tuberculosis granuloma: A systematic review and meta-analysis

2016

Infection with HIV-1 greatly increases the risk of active tuberculosis (TB). Although hypotheses suggest HIV-1 disrupts Mycobacterium tuberculosis (Mtb) granuloma function, few studies have examined this directly. The objective of...

Organization of care for persons with HIV-infection: A systematic review

2016

The objective of this systematic review was to examine the effectiveness of the organization of care: case management, multidisciplinary care, multi-faceted treatment, hours of service, outreach programs and health information...

Relationship-based predictors of sexual risk for HIV among MSM couples: A systematic review of the literature

2016

Behavioral and epidemiological studies report high risk for HIV among MSM couples. Over the last decade, studies have examined relationship dynamics associated with sexual risk for HIV. It is important...

A synthesis of meta-analytic evidence of behavioral interventions to reduce HIV/STIs

2016

To identify the mode of delivery, communicator, and content dimensions that make STI/HIV prevention interventions most successful at increasing condom use/protected sex or reducing STI/HIV incidence. A literature search for...

HIV self-testing: A review of current implementation and fidelity

2016

Oral HIV self-testing is an innovative and potentially high-impact means to increase HIV-case identification globally. As a screening test, oral HIV self-testing offers the potential for increased adoption through greater...

The effects of RANTES polymorphisms on susceptibility to HIV-1 infection and disease progression: Evidence from an updated meta-analysis

2016

Associations of regulated on activation, normal T cell expressed and secreted (RANTES) -403G/A, -28C/G and In1.1T/C polymorphisms with HIV-1 infection and the progression of HIV-1 disease have been widely reported...

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