SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A meta-analysis investigating incidence and features of stroke in HIV-infected patients in the highly active antiretroviral therapy era

2015

OBJECTIVE: Recent studies have suggested a close biological and clinical association between HIV infection and risk of myocardial infarction, whereas contrasting data have been reported about incidence of stroke and...

Providing comprehensive health services for young key populations: Needs, barriers and gaps

2015

INTRODUCTION: Adolescence is a time of physical, emotional and social transitions that have implications for health. In addition to being at high risk for HIV, young key populations (YKP) may...

Meta-analysis of studies comparing single and multi-tablet fixed dose combination HIV treatment regimens

2015

Availability of a single source review of once-daily fixed-dose single tablet regimen (STR) and multiple tablet fixed-dose regimen (MTR) would optimally inform healthcare providers and policy makers involved in the...

Single use of Iitraconazole has no effect on treatment for Penicillium marneffei with HIV infection

2015

OBJECTIVE: To evaluate the efficacy of a single use of itraconazole for treating Penicillium marneffei infection in HIV-infected patients, help to develop a clinical medication regimen, and provide a scientific...

Intimate partner violence and engagement in HIV care and treatment among women: A systematic review and meta-analysis

2015

OBJECTIVE: We aimed to estimate the odds of engagement in HIV care and treatment among HIV-positive women reporting intimate partner violence (IPV). DESIGN: We systematically reviewed the literature on the...

The impact of water, sanitation, and hygiene interventions on the health and well-being of people living with HIV: A systematic review

2015

BACKGROUND: Access to improved water supply and sanitation is poor in low-income and middle-income countries. Persons living with HIV/AIDS (PLHIV) experience more severe diarrhea, hospitalizations, and deaths from diarrhea because...

Retention of adult patients on antiretroviral therapy in low- and middle-income countries: Systematic review and meta-analysis 2008-2013

2015

BACKGROUND: We previously published systematic reviews of retention in care after antiretroviral therapy initiation among general adult populations in sub-Saharan Africa. We estimated 36-month retention at 73% for publications from...

Recent evidence for emerging digital technologies to support global HIV engagement in care

2015

Antiretroviral therapy is a powerful tool to reduce morbidity and mortality for the 35 million people living with HIV globally. However, availability of treatment alone is insufficient to meet new...

A systematic review of HIV and STI behavior change interventions for female sex workers in the United States

2015

The lives of female sex workers (FSW) in the US are typically marked by substance abuse, violence, trauma, and poverty. These factors place FSW at risk for acquiring and transmitting...

Rifapentine for latent tuberculosis infection treatment in the general population and human immunodeficiency virus-positive patients: Summary of evidence

2015

Latent tuberculosis infection (LTBI) and human immunodeficiency virus (HIV)-coinfection are challenges in the control of tuberculosis transmission. We aimed to assess and summarize evidence available in the literature regarding the...

CD4 changes among virologically suppressed patients on antiretroviral therapy: A systematic review and meta-analysis

2015

INTRODUCTION: The effectiveness of antiretroviral therapy (ART) is assessed by measuring CD4 cell counts and viral load. Recent studies have questioned the added value of routine CD4 cell count measures...

Treatment outcomes for HIV and MDR-TB co-infected adults and children: Systematic review and meta-analysis

2015

BACKGROUND: The incidence of multidrug-resistant tuberculosis (MDR-TB) is increasing in high human immunodeficiency virus (HIV) prevalence settings, with high associated mortality. Treatment outcomes in HIV-co-infected adults and children are poorly...

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