SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Incident fractures in HIV-infected individuals: A systematic review and meta-analysis

2013

OBJECTIVE(S): Some but not all studies indicate that individuals with HIV infection are at an increased risk of fracture. We systematically reviewed the literature to investigate whether incidence of fracture...

A meta-analysis of drug resistant tuberculosis in Sub-Saharan Africa: How strongly associated with previous treatment and HIV co-infection?

2013

BACKGROUND: In Sub-Saharan Africa, the fight against tuberculosis (TB) has encountered a great challenge because of the emergence of drug resistant TB strains and the high prevalence of HIV infection....

Alcohol use and sexual risk behaviors among individuals infected with HIV: A systematic review and meta-analysis 2012 to early 2013

2013

The purpose of this meta-analytic study is to summarize the current science concerning the (a) prevalence of alcohol use, (b) prevalence of sexual risk behaviors, and (c) association between alcohol...

Prevalence of HIV and syphilis infection among high school and college student MSM in China: A systematic review and meta-analysis

2013

OBJECTIVES: The aim of this study is to systematically review the published studies and summarize the estimates of HIV and syphilis prevalences among high school and college student MSM in...

The effects of viral load and antiretroviral medications on sexual transmission of HIV

2013

Key take-home messages Several studies have noted differences in viral load levels when comparing blood plasma to semen, cervicovaginal secretions and rectal mucosa. Despite an undetectable blood plasma viral load...

Effectiveness of sport-based HIV prevention interventions: A systematic review of the evidence.

2013

Interest in sport as a tool for behavioral HIV prevention has grown substantially in the past decade. With dozens of organisations now using sport-based HIV prevention (SBHP) approaches and upcoming...

Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis

2013

BACKGROUND: Currently, initiation of antiretroviral therapy (ART) in most patients with human immunodeficiency virus (HIV) infection is based on the CD4-positive-t-lymphocyte count. However, the point during the course of HIV...

Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV

2013

BACKGROUND: Regimen simplification can be defined as a change in established effective therapy to reduce pill burden and dosing frequency, to enhance tolerability, or to decrease specific food and fluid...

Smoking-cessation interventions in people living with HIV infection: A systematic review

2013

Tobacco smoking remains a prevalent behavior in people living with HIV infection (PLWHs) and is associated with impaired immune functioning, increased cardiovascular risk, and decreased response to antiretroviral therapy. This...

Cardiac dysfunction in pauci symptomatic human immunodeficiency virus patients: A meta-analysis in the highly active antiretroviral therapy era

2013

AIMS: Human immunodeficiency virus infection (HIV) has been associated with cardiac dysfunction that, if present, can negatively affect morbidity and mortality of HIV-infected patients. Unfortunately, many of the studies on...

How does the mining industry contribute to sexual and reproductive health in developing countries? A narrative synthesis of current evidence to inform practice

2013

AIMS AND OBJECTIVES: To explore client and provider experiences and related health outcomes of sexual and reproductive health interventions that have been led by or that have involved mining companies....

Tuberculosis, injecting drug use and integrated HIV-TB care: A review of the literature

2013

BACKGROUND: People who inject drugs (PWID) are at increased risk of tuberculosis (TB) and reduced retention in treatment. There is a need to document strategies for integrated delivery of HIV,...

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