SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Hormonal contraceptive use and female-to-male HIV transmission: A systematic review of the epidemiologic evidence

2013

OBJECTIVE: To systematically review epidemiologic evidence assessing whether hormonal contraception alters the risk of HIV transmission from an HIV-positive woman to an HIV-negative male partner. DESIGN: Systematic review. METHODS: We...

Female condom use for men who have sex with men

2013

Key take-home messages Men who have sex with men who have used a female condom often complain of irritation, bunching up, unpleasant texture, noise, discomfort upon insertion, lack of pleasure,...

State of the evidence: Intimate partner violence and HIV/STI risk among adolescents

2013

This paper provides a critical narrative review of the scientific literature on intimate partner violence (IPV) and risky sexual behavior as well as sexually transmitted infections (STIs) among adolescents, aged...

Tuberculosis, injecting drug use and integrated HIV-TB care: A review of the literature

2013

BACKGROUND: People who inject drugs (PWID) are at increased risk of tuberculosis (TB) and reduced retention in treatment. There is a need to document strategies for integrated delivery of HIV,...

Disclosure of HIV status to children in resource-limited settings: A systematic review

2013

Introduction: Informing children of their own HIV status is an important aspect of long-term disease management, yet there is little evidence of how and when this type of disclosure takes...

Treatment outcomes of treatment-naive Hepatitis C patients co-infected with HIV: A systematic review and meta-analysis of observational cohorts

2013

INTRODUCTION: Co-infection with Hepatitis C (HCV) and HIV is common and HIV accelerates hepatic disease progression due to HCV. However, access to HCV treatment is limited and success rates are...

Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV

2013

BACKGROUND: Regimen simplification can be defined as a change in established effective therapy to reduce pill burden and dosing frequency, to enhance tolerability, or to decrease specific food and fluid...

Complementary, alternative and traditional medicine in HIV care

2013

Key take-home messages Complementary and alternative medicine use among people living with HIV continues to be popular even though there are few methodologically rigorous studies documenting its effectiveness, and studies...

A review of medical and substance use co-morbidities in Central Asian prisons: Implications for HIV prevention and treatment

2013

BACKGROUND: HIV incidence in Central Asia is rising rapidly. People who inject drugs (PWIDs) contribute greatest to the epidemic, with more than a quarter of all HIV cases being in...

The other genome: A systematic review of studies of mitochondrial DNA haplogroups and outcomes of HIV infection and antiretroviral therapy

2013

Mitochondrial toxicity is implicated in some treatment-limiting antiretroviral therapy complications, and reports of mitochondrial dysfunction in untreated HIV infection suggest antiretroviral therapy independent effects of HIV. Several studies have explored...

Immunological and virological benefits resulted from short-course treatment during primary HIV infection: A meta-analysis

2013

OBJECTIVES: To assess the potential immunological and virological effects that result from short-course antiretroviral treatment during primary HIV infection (PHI). And to investigate whether treatment initiation time, treatment duration and...

Clinical use of HIV integrase inhibitors: A systematic review and meta-analysis

2013

BACKGROUND: Optimal regimen choice of antiretroviral therapy is essential to achieve long-term clinical success. Integrase inhibitors have swiftly been adopted as part of current antiretroviral regimens. The purpose of this...

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