SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Impact of hepatitis C co-infection on response to antiretroviral treatment

2012

The MONET study, comparing darunavir/ritonavir-based triple therapy and monotherapy, has found higher risk of failure in patients with positive HCV serology, but the effects of HCV co-infection on the efficacy...

Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings

2012

Efavirenz (EFV) is a non-nucleoside widely used as first-line therapy for HIV-1 infection. Most of the research available on EFV comes from trials performed in industrialized countries and only a...

Cardiovascular disease in Blacks with HIV/AIDS in the United States: A systematic review of the literature

2012

Objectives: Blacks in the United States bear a disproportionate burden of Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) and cardiovascular disease (CVD). It has been demonstrated that HIV/AIDS itself and...

Smoking cessation interventions in people with HIV/AIDS (Updated 2015)

2012

Key take-home messages Tobacco smoking is much more common among people living with HIV than in the general population. While most medical providers offer some form of smoking cessation services, AIDS service...

Pathologising healthy children? A review of the literature exploring the mental health of HIV-affected children in sub-Saharan Africa

2012

This article reviews the expanding body of literature that examines the mental health of HIV-affected children in sub-Saharan Africa. Focusing on primary research across disciplines and methodologies, the review examines...

Psychological trauma and PTSD in HIV-positive women: A meta-analysis

2012

Women bear an increasing burden of the HIV epidemic and face high rates of morbidity and mortality. Trauma has been increasingly associated with the high prevalence and poor outcomes of...

The impact of HIV clinical pharmacists on HIV treatment outcomes: A systematic review

2012

OBJECTIVE: Due to the rapid proliferation of human immunodeficiency virus (HIV) treatment options, there is a need for health care providers with knowledge of antiretroviral therapy intricacies. In a HIV...

Social and structural factors associated with HIV disease progression among illicit drug users: A systematic review

2012

OBJECTIVE: To systematically review factors associated with HIV disease progression among illicit drug users, focusing on exposures exogenous to individuals that likely shape access and adherence to HIV treatment. DESIGN:...

Genital ulcer disease treatment for reducing sexual acquisition of HIV

2012

BACKGROUND: Genital ulcer disease by virtue of disruption of the mucosal surfaces may enhance HIV acquisition. Genital ulcer disease treatment with resolution of the ulcers may therefore contribute in reducing...

Tesamorelin: A growth hormone-releasing factor analogue for HIV-associated lipodystrophy

2012

OBJECTIVE: To evaluate the efficacy and safety of tesamorelin, a growth hormone releasing factor analogue approved by the Food and Drug Administration in November 2010 for the treatment of lipodystrophy...

An updated systematic review and meta-analysis on the treatment of active tuberculosis in patients with HIV infection

2012

Background. Human immunodeficiency virus (HIV) infection increases the risk of poor outcomes in active tuberculosis. We updated a systematic review and meta-analysis assessing the effects of duration of rifamycins, schedule...

Use of the Internet for the surveillance and prevention of sexually transmitted diseases

2012

The Internet is a relatively new tool in the surveillance and prevention of sexually transmitted infections, and this review examines its global use in this regard. Much use has been...

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