SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Determinants of male involvement in maternal and child health services in sub-Saharan Africa: A review

2012

INTRODUCTION: Male participation is a crucial component in the optimization of Maternal and Child Health (MCH) services. This is especially so where prevention strategies to decrease Mother-to-Child Transmission (MTCT) of...

The impact of education on sexual behavior in sub-Saharan Africa: A review of the evidence

2012

Many studies have attempted to determine the relationship between education and HIV status. However, a complete and causal understanding of this relationship requires analysis of its mediating pathways, focusing on...

No association of abacavir use with myocardial infarction: Findings of an FDA meta-analysis

2012

BACKGROUND: Several studies have reported an association between abacavir (ABC) exposure and increased risk of myocardial infarction (MI) among HIV-infected individuals. Randomized controlled trials (RCTs) and a pooled analysis by...

Mindfulness-based therapy for people living with HIV

2012

Key take-home messages Findings from five systematic reviews evaluating mindfulness-based interventions (MBIs) — specifically mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) — have found beneficial effects on mental...

Association between the CD209 promoter -336A/G polymorphism and susceptibility to tuberculosis: A meta-analysis

2012

Background and objective: Dendritic cell-specific intracellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN), encoded by the CD209 gene, is a major Mycobacterium tuberculosis receptor on human dendritic cells. The potentially functional -336A/G...

The use of incentives to reinforce medication adherence

2012

Objective: Poor medication adherence is a longstanding problem, and is especially pertinent for individuals with chronic conditions or diseases. Adherence to medications can improve patient outcomes and greatly reduce the...

Contraception for the HIV-positive woman: A review of interactions between hormonal contraception and antiretroviral therapy

2012

Background. Preventing unintended pregnancy in HIV-positive women can significantly reduce maternal-to-child HIV transmission as well as improve the woman’s overall health. Hormonal contraceptives are safe and effective means to avoid...

Nonoccupational postexposure prophylaxis following sexual assault in industrialized low-HIV-prevalence countries: A review

2012

Although available for over a decade, use of nonoccupational postexposure prophylaxis (nPEP) remains controversial in the United States. There are concerns over sexual assault survivors’ adherence, or lack thereof, leading...

HIV testing in community settings in resource-rich countries: A systematic review of the evidence

2012

OBJECTIVES: Community HIV testing represents an opportunity for diagnosing HIV infection among individuals who may not have contact with health services, especially in hard-to-reach groups. The aim of this review...

Does genetic diversity of HIV-1 non-B subtypes differentially impact disease progression in treatment-naive HIV-1-infected individuals? A systematic review of evidence: 1996–2010

2012

With 88% of HIV-1-infected individuals living in areas of high prevalence of non-B subtypes and with expanded global access to antiretroviral treatment (ART), studying disease progression amongst non-B subtypes gains...

Primary drug resistance in South Africa: Data from 10 years of surveys

2012

HIV-1 transmitted drug resistance (TDR) could reverse the gains of antiretroviral rollout. To ensure that current first-line therapies remain effective, TDR levels in recently infected treatment-naive patients need to be...

Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings

2012

Efavirenz (EFV) is a non-nucleoside widely used as first-line therapy for HIV-1 infection. Most of the research available on EFV comes from trials performed in industrialized countries and only a...

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