SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV incidence estimation using the BED capture enzyme immunoassay: Systematic review and sensitivity analysis

2010

BACKGROUND: HIV incidence estimates are essential for understanding the evolution of the HIV epidemic and the impact of interventions. Tests for recent HIV infection allow incidence estimation based on a...

The utility of voluntary counselling and testing data as a source of information on HIV prevalence: A systematic review

2010

We explored the utility of routine HIV testing data from clinical services for estimating HIV prevalence. A systematic review identified 28 eligible publications, covering concentrated epidemics (16 of 28) and...

HIV risk behavior self-report reliability at different recall periods

2010

Few studies have investigated the optimal length of recall period for self-report of sex and drug-use behaviors. This meta-analysis of 28 studies examined the test-retest reliability of three commonly used...

Monoclonal CCR5 antibody for treatment of people with HIV infection

2010

BACKGROUND: A monoclonal CCR5 antibody, PRO 140 (a humanised form of the PA14 antibody), inhibits CCR5-tropic (R5) HIV-1. This may be an effective new treatment for HIV-infected patients, with the...

Economic evaluations of adult male circumcision for prevention of heterosexual acquisition of HIV in men in sub-Saharan Africa: A systematic review

2010

Background: There is conclusive evidence from observational data and three randomized controlled trials that circumcised men have a significantly lower risk of becoming infected with the human immunodeficiency virus (HIV)....

Standard care impact on effects of highly active antiretroviral therapy adherence interventions: A meta-analysis of randomized controlled trials

2010

BACKGROUND: Poor adherence to medication limits the effectiveness of treatment for human immunodeficiency virus. Systematic reviews can identify practical and effective interventions. Meta-analyses that control for variability in standard care...

Safety and efficacy of nontherapeutic male circumcision: A systematic review

2010

PURPOSE: We wanted to assess the safety and efficacy of nontherapeutic male circumcision through a systematic review of the literature. METHODS: We systematically searched The York Centre for Reviews and...

Sports and social gay networks for HIV prevention

2010

Key take-home messages We were unable to locate any research evidence assessing sport and/or social gay networks as HIV prevention strategies. The studies we did identify assess social networks as...

Elite controllers for HIV

2010

Key take-home messages Elite control of HIV is very rare. There is no single mechanism to explain viral control in ECs that has been identified. Further study of how ECs...

Women experience higher rates of adverse events during Hepatitis C virus therapy in HIV infection: A meta-analysis

2010

Background: In HIV/HCV coinfection, adverse events (AE) during HCV therapy account for 12-39% of treatment discontinuations. It is unknown whether sex influences complications. Methods: Meta-analysis to study the effect of...

Safety of efavirenz in first-trimester of pregnancy: A systematic review and meta-analysis of outcomes from observational cohorts

2010

Introduction: Data on efavirenz safety in first trimester pregnancy are conflicting. We conducted a systematic review and meta-analysis of the available evidence from observational cohorts., Methods: We ran duplicate searches...

The cost of treatment and care for people living with HIV infection: Implications of published studies, 1999-2008

2010

Purpose of review: Increasing number of people living with HIV (PLHIV) will require expanded access to health services. Countries need robust and contemporary strategic information on the cost of care...

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