SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effect of directly observed therapy for highly active antiretroviral therapy on virologic, immunologic, and adherence outcomes: A meta-analysis and systematic review

2010

Introduction: Directly observed therapy of highly active antiretroviral therapy (DOT-HAART) is a feasible adherence intervention. Prospective DOT-HAART studies have shown mixed results, and optimal target groups have yet to be...

HIV, poverty and women

2010

This review examines the interactions of financial status and HIV and its implications for women. MEDLINE and Google scholar were searched using the keywords ‘women’, ‘poverty’ and ‘HIV’ in any...

The impact of disease stage on direct medical costs of HIV management: A review of the international literature

2010

The global prevalence of HIV infection continues to grow, as a result of increasing incidence in some countries and improved survival where highly active antiretroviral therapy (HAART) is available. Growing...

Home-based care for reducing morbidity and mortality in people infected with HIV/AIDS

2010

BACKGROUND: Home-based care (HBC), to promote quality-of-life and limit hospital care, is used in many countries, especially where public health services are overburdened. OBJECTIVES: This review assessed the effects of...

Applicability and generalisability of the results of systematic reviews to public health practice and policy: A systematic review

2010

BACKGROUND: The purpose of the study was to evaluate systematic reviews of research into two public health priorities, tobacco consumption and HIV infection, in terms of the reporting of data...

Optimal time for initiation of antiretroviral therapy in asymptomatic, HIV-infected, treatment-naive adults

2010

BACKGROUND: According to consensus, initiation of therapy is best based on CD4 cell count, a marker of immune status, rather than on viral load, a marker of virologic replication. For...

Health outcomes associated with methamphetamine use among young people: A systematic review

2010

OBJECTIVES: Methamphetamine (MA) use among young people is of significant social, economic and public health concern to affected communities and policy makers. While responses have focused upon various perceived severe...

A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization

2010

BACKGROUND: Alcohol use disorders (AUDs) are highly prevalent and associated with non-adherence to antiretroviral therapy, decreased health care utilization and poor HIV treatment outcomes among HIV-infected individuals. OBJECTIVES: To systematically...

Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis

2010

BACKGROUND: Patients with human immunodeficiency virus (HIV) infection and tuberculosis have an increased risk of death, treatment failure, and relapse. METHODS: A systematic review and meta-analysis of randomized, controlled trials...

Latino men and coming out

2010

Key take-home messages Further research is required to fully demonstrate the differences in ‘coming out’ patterns between Latino and White MSM and how these differences impact health, HIV outcomes and...

CCL3L1 copy number variation and susceptibility to HIV-1 infection: A meta-analysis

2010

Although several studies have investigated whether CCL3L1 copy number variation (CNV) influences the risk of HIV-1 infection, there are still no clear conclusions. Therefore, we performed a meta-analysis using two...

Economic evaluation, human immunodeficiency virus infection and screening: A review and critical appraisal of economic studies

2010

OBJECTIVES: The aim of this study was to review, systematically and critically, evidence used to derive estimates of cost-effectiveness of human immunodeficiency virus (HIV) screening. METHODS: A systematic review was...

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