SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Treatment for leiomyosarcoma and leiomyoma in children with HIV infection

2010

BACKGROUND: Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV...

Sexual risk reduction interventions for patients attending sexually transmitted disease clinics in the United States: A meta-analytic review, 1986 to early 2009

2010

Sexually transmitted disease (STD) patients are more likely to experience a future STD including human immunodeficiency virus (HIV). The aim of this study was to examine the efficacy of behavioral...

The prevalence of sexually transmitted infections in Papua New Guinea: A systematic review and meta-analysis

2010

BACKGROUND: The potential for an expanded HIV epidemic in Papua New Guinea (PNG) demands an effective, evidence-based and locally-appropriate national response. As sexually transmitted infections (STIs) may be important co-factors...

Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: A systematic review

2010

Following large-scale roll-out of antiretroviral therapy in sub-Saharan Africa, the non-clinical efficacy of antiretroviral therapy has received little attention. We aimed to systematically review virological efficacy and drug-resistance outcomes of...

Immune reconstitution inflammatory syndrome associated with Mycobacterium tuberculosis infection: A systematic review

2010

HIV and tuberculosis (TB) are leading global causes of mortality and morbidity. Highly active antiretroviral therapy (HAART) is often initiated in patients being treated for TB. The immune recovery associated...

Effectiveness and cost-effectiveness of pre- & post-exposure prophylaxis for HIV

2010

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis

2010

The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...

HIV status in discordant couples in sub-Saharan Africa: A systematic review and meta-analysis

2010

BACKGROUND: Most couples affected by HIV/AIDS in sub-Saharan Africa live in discordant relationships. Men are thought to be the index case in most relationships, and most social marketing and awareness...

Coordination and delivery of HIV prevention, treatment, care and support by nurse practitioners

2010

Key take-home messages • Medical care, including primary care, delivered by nurse practitionersis often equivalent to the care administered by physicians. Caredelivered by nurse practitioners generally rates higher on measures...

The expanding epidemics of HIV type 1 among men who have sex with men in low- and middle-income countries: Diversity and consistency

2010

Men who have sex with men (MSM) have borne a disproportionate burden of human immunodeficiency virus (HIV) infection and remain a markedly underresourced population globally. To better describe HIV epidemics...

Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus

2010

BACKGROUND: Antiviral treatment for chronic hepatitis C may be less effective if patients are co-infected with human immunodeficiency virus (HIV). OBJECTIVES: To assess the benefits and harms of antiviral treatment...

Syphilitic uveitis: A review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients

2010

The incidence of syphilis and syphilitic uveitis in our community is increasing. The prevalence of associated neurosyphilis is unknown, and it remains unclear whether syphilitic uveitis should be treated as...

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