SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effectiveness and impact of using the internet for prevention of HIV/AIDS

2009

Key take-home messages The Internet is a feasible channel to deliver HIV prevention and intervention. With the internet increasingly used not only for meeting sex partners but also for finding...

Interventions for preventing late postnatal mother-to-child transmission of HIV

2009

BACKGROUND: Worldwide, mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV) represents the most common means by which children acquire HIV infection. Efficacious and effective interventions to prevent in...

Behavioral interventions for African Americans to reduce sexual risk of HIV: A meta-analysis of randomized controlled trials

2009

CONTEXT: African Americans constitute 13% of the US population yet account for nearly 50% of new HIV infections. Implementation of efficacious behavioral interventions can help reduce infections in this vulnerable...

Effectiveness of pediatric antiretroviral therapy in resource-limited settings: A systematic review and meta-analysis

2009

BACKGROUND: Responses to antiretroviral therapy (ART) among human immunodeficiency virus (HIV)-infected children in resource-limited settings have recently been reported, but outcomes vary. We sought to derive pooled estimates of the...

Deworming helminth co-infected individuals for delaying HIV disease progression

2009

BACKGROUND: The HIV-1 pandemic has disproportionately affected individuals in resource-constrained settings. These areas often also have high prevalence of other infectious diseases, such as helminth infections. It is important to...

HIV-1 and intestinal helminth review update: Updating a Cochrane Review and building the case for treatment and has the time come to test and treat?

2009

Intestinal helminth infection activates and dysregulates the immune system and impacts the host’s capacity to respond to illness. Such neglected tropical infections exact the greatest burden on resource-limited settings and...

Mortality of patients lost to follow-up in antiretroviral treatment programmes in resource-limited settings: Systematic review and meta-analysis

2009

Background: The retention of patients in antiretroviral therapy (ART) programmes is an important issue in resource-limited settings. Loss to follow up can be substantial, but it is unclear what the...

Apricitabine: A nucleoside reverse transcriptase inhibitor for HIV infection

2009

OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of apricitabine, a nucleoside reverse transcriptase inhibitor that is currently under investigation and has fast-track approval status with the Food and...

A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals

2009

OBJECTIVE: To estimate summary standardized incidence ratios (SIRs) of non-AIDS cancers among HIV-infected individuals compared with general population rates overall and stratified by gender, AIDS, and highly active antiretroviral therapy...

HIV medication and depression

2009

Key take-home messages The Ontario HIV and Substance Use Training Program offers workshops across Ontario for counselors working in the field. In the past these workshops have advised counselors to...

Efficacy and tolerability of initial antiretroviral therapy: A systematic review

2009

OBJECTIVES: Successful antiretroviral therapy (ART) is largely attributed to the type of third drug. Guidelines recommend regimens without systematic review of all factors that might affect treatment success, such as...

The epidemiology of human immunodeficiency virus infection, sexually transmitted infections, and associated risk behaviors among men who have sex with men in the Mekong Subregion and China: implications for policy and programming

2009

BACKGROUND: Little systematic knowledge is available regarding risk behaviors and the prevalence of human immunodeficiency virus (HIV) and sexually transmitted infections (STI) in populations of men having sex with men...

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