SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse transcriptase inhibitors: Indirect comparison of controlled trials

2004

Objective: To compare the clinical efficacy of triple antiretroviral regimens based on protease inhibitors and non-nucleoside analogue reverse transcriptase inhibitors (NNRTIs) in adults positive for antibodies to HIV-1. Design: Systematic...

School-based HIV prevention programmes for African youth

2004

The high rate of HIV infection among youth in Africa has prompted both national and international attention. Education and prevention programmes are seen as the primary way of decreasing this...

Effectiveness of aerobic exercise in adults living with HIV/AIDS: Systematic review

2004

PURPOSE: The objective of this systematic review was to examine the effectiveness and safety of aerobic exercise interventions on immunological/virological, cardiopulmonary, and psychological outcomes in adults living with HIV/AIDS. METHODS:...

Interventions to prevent HIV/AIDS among adolescents in less developed countries: Are they effective?

2004

The objective of this study was to summarize and critically assess the effects of interventions to prevent HIV/AIDS among adolescents in less developed countries. Reports of studies that evaluated interventions...

Prevalence and outcomes of anemia in individuals with human immunodeficiency virus: A systematic review of the literature

2004

In patients with human immunodeficiency virus (HIV), anemia is a commonly encountered hematologic abnormality that has a significant impact on clinical outcomes and quality of life (QOL). This review describes...

Treatment outcomes after highly active antiretroviral therapy: A meta-analysis of randomised controlled trials

2004

This systematic review summarises the evidence for treatment efficacy and tolerability of highly active antiretroviral therapies containing two nucleoside reverse transcriptase inhibitors (NRTI) with a protease inhibitor (PI), compared with...

Fosamprenavir: A review of its use in the management of antiretroviral therapy-naive patients with HIV infection

2004

Fosamprenavir (GW433908, Lexiva, Telzir) is an oral prodrug of the protease inhibitor (PI) amprenavir, with a reduced daily pill burden. Fosamprenavir, in combination with other antiretroviral agents, is indicated for...

Behavioral interventions to reduce incidence of HIV, STD, and pregnancy among adolescents: A decade in review

2004

PURPOSE: To review adolescent sexual risk-reduction programs that were evaluated using quasi-experimental or experimental methods and published in the 1990s. We describe evaluated programs and identify program and evaluation issues...

Pharmacologic therapy for HIV-associated lipodystrophy

2004

OBJECTIVE: To evaluate the efficacy and safety of pharmacologic therapy in the treatment of HIV-associated lipodystrophy, with a focus on the treatment of fat redistribution. Drug therapies that have been...

HIV health promotion and men who have sex with men (MSM): A systematic review of research relevant to the development and implementation of effective and appropriate interventions

2004

This review evaluated the effectiveness of HIV-related health promotion interventions in men who have sex with men. The authors concluded that cognitive-behavioural-based counselling or workshops can reduce incidences of unprotected...

Global strategies to prevent bacterial pneumonia in adults with HIV disease

2004

We examined the peer-reviewed literature on the burden of bacterial pneumonia and the effectiveness of interventions for its prevention among HIV-infected adults in developed and developing countries. Bacterial pneumonia rates...

Stigma in HIV-Positive women

2004

Purpose: To present a metasynthesis of qualitative findings on stigma in HIV-positive women. Method: Metasummary and metasynthesis techniques were used to integrate findings on stigma in 93 reports of qualitative...

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