SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Fosamprenavir: A review of its use in the management of antiretroviral therapy-naive patients with HIV infection

2004

Fosamprenavir (GW433908, Lexiva, Telzir) is an oral prodrug of the protease inhibitor (PI) amprenavir, with a reduced daily pill burden. Fosamprenavir, in combination with other antiretroviral agents, is indicated for...

HIV health promotion and men who have sex with men (MSM): A systematic review of research relevant to the development and implementation of effective and appropriate interventions

2004

This review evaluated the effectiveness of HIV-related health promotion interventions in men who have sex with men. The authors concluded that cognitive-behavioural-based counselling or workshops can reduce incidences of unprotected...

Behavioral interventions to reduce incidence of HIV, STD, and pregnancy among adolescents: A decade in review

2004

PURPOSE: To review adolescent sexual risk-reduction programs that were evaluated using quasi-experimental or experimental methods and published in the 1990s. We describe evaluated programs and identify program and evaluation issues...

Pharmacologic therapy for HIV-associated lipodystrophy

2004

OBJECTIVE: To evaluate the efficacy and safety of pharmacologic therapy in the treatment of HIV-associated lipodystrophy, with a focus on the treatment of fat redistribution. Drug therapies that have been...

Global strategies to prevent bacterial pneumonia in adults with HIV disease

2004

We examined the peer-reviewed literature on the burden of bacterial pneumonia and the effectiveness of interventions for its prevention among HIV-infected adults in developed and developing countries. Bacterial pneumonia rates...

Stigma in HIV-Positive women

2004

Purpose: To present a metasynthesis of qualitative findings on stigma in HIV-positive women. Method: Metasummary and metasynthesis techniques were used to integrate findings on stigma in 93 reports of qualitative...

A review of research on residential programs for people with severe mental illness and co-occurring substance use disorders

2004

Substance use disorder is the most common and clinically significant co-morbidity among clients with severe mental illnesses, associated with poor treatment response, homelessness and other adverse outcomes. Residential programs for...

Recreational use of sildenafil by HIV-positive and -negative homosexual/bisexual males

2004

OBJECTIVE: To conduct an epidemiologic review of sildenafil in homosexual and bisexual males focusing on concurrent use with club drugs and/or antiretroviral medications. DATA SOURCES: A search of MEDLINE was...

Barriers to participating in an HIV vaccine trial: A systematic review

2004

The enrolling of adequate participants into HIV experimental drug trials presents an important challenge. We systematically reviewed the literature to identify barriers and concerns amongst HIV patients to participation in...

Atazanavir: A new protease inhibitor to treat HIV infection

2004

PURPOSE: The pharmacology, pharmacokinetics, and clinical trials of and drug interactions and formulary considerations associated with atazanavir, the newest protease inhibitor (PI) to treat human immunodeficiency virus (HIV) infection, are...

HIV: Associated transmission risks in older adults – An integrative review of the literature

2004

Recent evidence suggests that transmission of human immunodeficiency virus (HIV) is increasing among late middle-aged and older adults (50 years of age or older). However, research studies explaining the unique...

Changes in the human immunodeficiency virus V3 region that correspond with disease progression: A meta-analysis

2004

In order to determine the changes in the human immunodeficiency virus type-1 (HIV-1) envelope that corresponds with disease progression, a meta-analysis of viral forms was performed using HIV-1 sequences obtained...

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