SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The level of antiretroviral therapy (ART) adherence among orphan children and adolescents living with HIV/AIDS: A systematic review and meta-analysis

2024

Background Many children and adolescents living with HIV have ended up as orphans. Due to HIV taking away their parents leaves them deprived of their most important social network and...

Prevalence of delayed treatment for sexually transmitted infections and its determinants in sub-Saharan Africa. A systematic review and meta-analysis

2024

BACKGROUND: Sexually transmitted infection is a common public health issue, and it is characteristically transmitted through sexual intercourse. Around the globe, particularly in less developed countries, delayed treatment of this...

Men who have sex with men perceiving that sex with women carries the greatest risk of HIV acquisition: Results from a mixed-methods systematic review in sub-Saharan Africa

2024

INTRODUCTION: In sub-Saharan Africa (SSA), men who have sex with men (MSM) often have female sexual partners. Their overall risk of acquiring HIV is higher with male partners. Risk perception...

Level of adherence to option B+ program and associated factors among HIV-positive women in Ethiopia: A systematic review and meta-analysis

2024

BACKGROUND: Despite policy initiatives and strategic measures highly focused on preventing mother-to-child transmission through the implementation of the Option B+ program, adherence to the treatment is still challenging. The level...

Risk of viral failure after simplification therapy without using integrase inhibitors compared with maintenance of triple antiretroviral therapy: A systematic review and meta-analysis

2024

Background Antiretroviral drug simplification is a strategy to reduce drug exposure and improve treatment adherence. Nowadays, dolutegravir plus lamivudine is the most preferred regimen, which might lead in the future...

Person-centred interventions to improve patient-provider relationships for HIV services in low- and middle-income countries: A systematic review

2024

INTRODUCTION: Person-centred care (PCC) has been recognized as a critical element in delivering quality and responsive health services. The patient-provider relationship, conceptualized at the core of PCC in multiple models,...

Point of care HIV testing in dental settings in high-income countries: A mixed-methods systematic review

2024

Objectives: Expanding HIV testing beyond specialized services has been a key strategic approach to eliminating the transmission of HIV. In recent years, dental settings have been identified as offering an opportunity...

Molecular detection of rifampicin-resistant Mycobacterium tuberculosis by polymerase chain reaction in Ethiopia: A systematic review and meta-analysis

2024

INTRODUCTION: Tuberculosis is a contagious bacterial disease caused by Mycobacterium tuberculosis. The emergence and spread of drug-resistant strains of M. tuberculosis in both developing and developed countries has made diagnosis,...

The spectrum of health conditions in community-based cross-sectional surveys in Southeast Asia 2010–21: A scoping review

2024

Background Southeast Asia is undergoing an epidemiological transition with non-communicable illnesses becoming increasingly important, yet infectious diseases (tuberculosis, HIV, hepatitis B, malaria) remain widely prevalent in some populations, while emerging...

Innovation and implementation determinants of HIV testing and linkage-to-care in the U.S.: A systematic review

2024

OBJECTIVE: To identify innovation and implementation determinants of HIV testing, diagnosis, and linkage-to-care in the U.S. DATA SOURCES AND STUDY SETTING: Between November 2020 and January 2022, a broad search...

Pre-exposure prophylaxis adherence among men who have sex with men: A systematic review and meta-analysis

2024

OBJECTIVES: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of HIV among men who have sex with men (MSM) relies on how widely it is adopted...

Regional variation in NAFLD prevalence and risk factors among people living with HIV in Europe: A meta-analysis

2024

BACKGROUND AND AIM: Europe faces an elevated risk of nonalcoholic fatty liver disease (NAFLD) among people living with HIV (PLWH), contributing to the region’s highest global burden of NAFLD. However,...

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